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6 classes of alkylating agents nitrogen mustards, ethylenimines, nitroureas, alkyl sulfonates, triazenes, and platinum analogues
5 nitrogen mustards chlorambucil, cyclphosphamide, ifosfamide, melphalan, mechlorethamine
1 ethylenimines thiotepa
4 nitrosoureas carmustine, lomustine, semustine, streptozocin
1 alkyl sulfonates busulfan
2 triazenes dacarbazine, temozolamide
3 platinum analogues cisplatin, carboplatin, oxaliplatin
3 classes of topoisomerase II inhibitors anthracyclines, epipodophyllotoxins, miscellaneous
4 anthracyclines daunorubincin, doxorubicin, idarubicin, epirubicin
2 epipodophyllotoxins etoposide, tenoposide
1 miscellaneous topoisomerase II inhibitor mitoxantrone
1 class of topoisomerase I inhibitor camptothecins
2 camptothecins irinotecan, topotecan
3 classes of antimicrotubules vinca alkaloid, taxanes, epothilones
3 vinca alkaloids vinblastine, vincristine, vinorelbine
3 taxanes paclitaxel, docetaxel, cabazitaxel
1 epothilones ixabepilone
3 classes of antimetabolites folate antagonist, purine analogues, pyrimidine analogues
2 folate antagonist MTX, pemetrexed
5 purine analogues cladribine, fludarabine, mercaptopurine, pentostatin, thioguanine
4 pyrimidine analogues cytarabine, gemcitabine, fluorouricil, capecitabine
5 classes of hormonal agents antiestrogens, aromatase inhibitors, LH-RH antagonists, antiandrogens, miscellaneous hormonal agents
2 antiestrogens tamoxifen, megestrol acetate
4 aromatase inhibitors aminoglutethimide, anastrozole, letrozole, exemestane
2 LH-RH antagonist goserelin, leuprolide
3 antiandrogens bicalutamide, flutamide, nilutamide
1 miscellaneous hormonal agent estramustine
2 classes of targeted therapies monoclonal antibodies, tyrosine kinase inhibitors
7 monoclonal antibodies gentuzumab, alemtuzumab, rituximab, ibritumomab, tositumomab, trastuzumab, cetuximab
3 tyrosine kinase inhbitors erlotinib, gefitinib, imatinib
4 miscellaneous chemotherapy agents bortezomib, denileukin, bleomycin sulfate, thalidomide
Created by: templets