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bacterial coverage

bacterial coverage by class

Carboxy-penicillins (Carbenicillin, Ticarcillin) Streptococcal Spp., EXCELLENT gram negative activity (including pseudomonas) (Ticarcillin > Carbenicillin against pseudomonas) Intermediate enterococcus spp. coverage N/A
Ureido-Penicillins (Azlocillin, Mezocillin, Piperacillin) Streptcoccal spp., Enterococcus spp., BL-S. aureus, EXCELLENT gram negative activity (including pseudomonas - better than carboxy) Some against gram negative anaerobes (including bacteroides fragilis) N/A
Beta-lactam combos (unasyn, augmentin, tymentin, zosyn) extended gram negative (but not pseudomonas) extended gram positive (Includes MSSA but not MRSA), Extended gram negative anaerobic bacilli N/A N/A
Penicillins Overall GRAM + aerobes super good, Most cover enterococcus except nafcillin, dicloxacillin, and carbenicillin) NO MRSA NO Atypicals
1st Generation Cephalosporin (Cefazolin, cephalexin, cefadroxil) Streptcoccal spp. MSSA limited gram negative NO enterococcal
2nd Generation Cephalosporin, group 1 (Cefuroxime, cefaclor) streptoccal spp. MSSA limited gram negative (E. coli, H. influenzae, K. pneumoniae) NO enterococcal NO pseudomonas No gram negative
2nd Generation Cephalosporin, group 2 (Cefoxitin, Cefotetan, Cemetazole) Enhanced activity against enterobacteriaeceae Limited streptococcal spp. limited MSSA NO enterococcal no pseudomonas
3rd Generation Cephalosporin, (normal) (Ceftriaxone, Cefixime, Cefpodoxime proxetil) Excellent streptoccal spp. activity, Excellent gram negative activity (E. coli, H. influenzae, K pneumoniae, Proteus spp) moderate MSSA activity NO enterococcal no pseudomonas little to no gram negative anaerobic activity
3rd generation cephalosporin (antipseudomonal) (Ceftazidime, Cefoperazone) NO enterococcal
4th Generation Cephalosporin (Cefepime) NO enterococcal
5th Generation Cephalosporin (Ceftaroline) NO enterococcal
Cephalosporins overall Gram + aerobes Most cover MSSA (not so much ceftazidime) Most cover gram negative aerobes No enterococcus No MRSA (EXCEPT ceftaroline) NO Gram negative anaerobes (except cefoxitin) No atypicals
Natural Penicillins (Penicillin G and Penicillin V) Streptococcal spp. Enterococcus spp. Treponema pallidum(DOC), Cover SOME: anaerobic streptococci (peptococcus and peptostreptococcus) NO Gram negative, NO pseudomonas aeruginosa
Aminopenicillins (Ampicillin and amoxicillin) same as natural penicillins (Streptococcal spp., Enterococcus spp., Treponema pallidum) but, EXTENDED gram negative (H. influenzae, E. coli, K. pneumoniae), -enhanced activity against enterococcus spp. NO N/A No pseudomonas aeruginosa
Penicillinase Resistant Penicillins (Oxacillin, nafcillin, cloxacillin, dicloxacillin) Streptococcal spp. Staphlococcus aureus (DOC for MSSA) N/A NO gram negative (including pseudomonas) NO MRSA, NO Enterococcus
Created by: HugsAndKisses