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Pima Cardiopulm. 7,8

Stack #121551

QuestionAnswer
ODC shift left More alkalosis, less DPG, hemoglobin has more affinity for O2, P50 decreases, Hgb is more saturated at a given PO2.
ODC shift right More acidic, more DPG, hemoglobin has less affinity for O2, P50 increases, Hgb is less saturated at a given PO2.
Normal P50 27mmHg
CO2 diffusion rate 20 times faster than O2
Dead space anatomic 1ml per pound, alveolar dead space can not be calculated, physiological dead space the sum of alveolar and anatomical deadspace.
Anatomic Shunt (true shunt) The portion of cardiac output that enters the left side of the heart without comming in contact with an alveolus for gas exchange.
Causes of Anatomic Shunts Congenital heart disease, Intrapulmonary fistula, Vascular tumors.
Capillary Shunt (true shunt) No gas exchange at alveoli.
Absolute shunt When more O2 doesn't help/ refractory to oxygen therapy.
Shunt-like effect When pulmonary capillary perfusion is in excess of alveolar ventilation.
Causes of Capillary Shunts Atelectasis, alveolar fluid accumulation, or consolidation.
% of total CO2 transported to the lungs in RBC's by bicarbonate (HCO3) 63%
The Haldane Effect Deoxygenated blood enhances loading of CO2 and oxyegnated blood enhaces the offload of CO2.
The Bohr Effect The effect of PCO2 and PH on the oxyhemoglobin curve.
Anatomic Shunt normals 2 to 5%
Things that move ODC right Temp increase, PCO2 increase, PH decrease (more H+), DPG increase.
Created by: pima respiratory