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Exam 2 Drugs.
Pharmacology
| Question | Answer |
|---|---|
| phenytoin | anti-epileptic, prolongation of Na channel inactivation |
| carbamaepine | anti-epileptic, prolongation of Na channel inactivation |
| valproate | anti-epileptic, prolongation of Na channel inactivation, supression of ca influx |
| lamotrigine | anti-epileptic, prolongation of Na channel inactivation |
| ethosuximide | anti-epileptic, suppression of ca influx |
| tiagabine | anti-epileptic, increased GABA action by prolonging presence of GABA in the synapse |
| vigabatrin | anti-epileptic, increased GABA action by inhibiting the enzyme that degrades GABA |
| thiopental | IV general anesthetic, produces unconisiousness in 10-30 sec |
| etomidate | IV general anesthetic, primarily for patients at risk for hypotension |
| propofol | IV general anesthetic |
| ketamine | IV general anesthetic |
| opium | the product of poppy plant and contains psychoactive substances including morphine, codeine, thebaine, papaverine, and noscapine |
| opiates | opium and its constituents and their semi-synthetic derivatives (heroin) |
| opiods | opiates and related synthetic substances (fentanyl, oxycodone) |
| morphine | strong agonist, analgesics |
| heroin | strong agonist, analgesics |
| hydromorphone (dilaudid) | strong agonist, analgesics |
| oxymorphone (dolophine) | strong agonist, analgesics |
| meperidine (demerol) | strong agonist, analgesics |
| fentanyl (sublimaze) | strong agonist, analgesics, Duragesic, Actiq |
| levorphanol (levo-dromoran) | strong agonist, analgesics |
| codeine | mild-moderate agonist, analgesics |
| oxycodone (oxycontin) | mild-moderate agonist, analgesics, dispensed aspirin, APAP, Ibu |
| hydrocodone (vicodin) | mild-moderate agonist, analgesics, dispensed with APAP or Ibu |
| propoxyphene (darvon) | mild-moderate agonist, analgesics, dispensed alone or incombination with aspirin and caffeine or APAP |
| pentazocine (talwin) | agonist-antagonist opioid, analgesic |
| butorphanol (stadol) | agonist-antagonist opioid, analgesic |
| Buprenorphine (buprenex, suboxone) | partial agonists, analgesics |
| naloxone | central/peripheral opioid antagonists, treat opioid toxicity |
| naltrexone | central/peripheral opioid antagonists, treatment of opioid addiction |
| methylnaltrexone | peripheral opioid antagonists, treat opioid induced constipation |
| alvimopan | peripheral opioid antagonists, treat opioid induced constipation |
| tramadol | atypical opioid, activate U, inhibit NE and 5-HT |
| tapentadol | atypical opioid, activate u, NE reuptake inhibitor |
| gabapentin | anticonvulsants, neuropathic pain and epilepsy |
| pregabalin | anticonvulsants, neuropathic pain and epilepsy |
| paroxetine | antidepressants |
| duloxetine | antidepressant, diabetic neuropathy, depression, fibromyalgia, chronic musculoskeletal pain, SNRI |
| ziconotide | n type calcium channel blocker, for severe chronic pain |
| sumatriptan | migraine |
| zolmitriptan | migraine |
| amphetamine (benzedrine) | racemic mixture |
| D-amphetamine (dexedrine) | dextroamphetamine |
| methylphenidate (ritalin) | attention deficit disorder |
| fenfluramine (redux) | anorectic |
| phenmetrazine (preludin) | anorectic |
| nicotine | nicotinic acetylcholine receptor agonist, acts on adrenal glands to induce epi release |
| bupropion (zyban, wellbutrin) | NET/DAT inhibitor, treats nicotine cravings and withdrawal |
| varenicline (chantix) | smoking cessation |
| acamprosaate (campral) | alcoholism treatment, does not prevent withdrawal |
| disulfram (antabus) | alcholism treatment, inhibitor of acetaldehyde dehydrogenase |
Created by:
Kachmiel
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