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gigi lim

medication its influence

define pharmocodynamics? how a drug influences cell physiology
define pharmocodynamics mechanism of action...of a drug
define pharmacokinetics? how the drug enters my body, reach site of action then eliminated from my body.
name a type of pharmacological action? drugs which change the environment of body cells eg antacids/mylanta>neutralising stomach acidity.
name a type of pharmacological action? the drug binding to the receptors causing a physiological response.
name a type of pharmacological action? a pts functional state can influence that response...not absorbed/inactivated once absorbed.
what is absorption? what happens to a drug from the time it enters the body until it enters the circulating fluid.
what is absorption? iv will bypass the complication of absorption from other routes.
explain active transport the movement of substances across the cell membranne.
an agonist is? a drug that interacts directly with a receptor site to cause an effect. eg
an agonist is? Drugs generally work by interacting with receptors on the surface of cells or enzymes (which regulate the rate of chemical reactions) within cells.This is often referred to as a lock and key model.
an agonist is? Examples of agonists are morphine, nicotine, phenylephrine, and isoproterenol
an agonist is? Receptor and enzyme molecules have a specific three-dimensional structure which allows only substances that fit precisely to attach to it. This is often referred to as a lock and key model.
an agonist is? Most drugs work because by binding to the target receptor site, they can either block the physiological function of the protein, or mimics it's effect.
an agonist is? If a drug causes the protein receptor to respond in the same way as the naturally occurring substance, then the drug is referred to as an agonist.
describe excretion? removal of a drug from the body starts in the kidneys...can also occur through the skin, bile as in vomitting, lungs and feces.
an antagonist does what? a drug that interacts with a receptor but does not cause an effect, but blocks it.
an antagonist does what? they reduce the action of an agonist at the receptor site involved.
an antagonist does what? Receptor antagonists can be classified as reversible or irreversible.
an antagonist does what? Examples of antagonist drugs are: beta-blockers, such as propranolol.
explain distribution? the movement of a drug to body tissues. this drug distribution is dependant on the drugs solubility, perfusion of the area, cardiac output and plasma binding.
what is 'first pass effect'? the first pass effect allows the liver to metabolise or inactivate drugs and potentially harmful substances before distribution throughout the body.
what is 'first pass effect'? Metabolism of a drug during its passage from site of absorption [GI tract] into the systemic circulation [bloodstream]. Enter the liver via the hepatic portal vein before entering general circulation.
Created by: aniwa