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Alpha & Beta Blocker
Pharmacolgy Exam 2
| Question | Answer |
|---|---|
| If you block the Alpha 1 receptor, what would you expect to happen? | Decreased blood pressure (vasodilation), decreased heart rate, and increase the ability to void the bladder |
| What is Phenoxybenzamine, an alpha 1 antagonist, used in the treatment of? | pheochromocytoma - a cancer that causes increases in circulating catecholamines, so blood pressure goes up radically. Phenoxybenzamine works to bring the BP back down to normal. |
| What is Phentolamine, an alpha 1 antagonist, used in the treatment of? | pheochromocytoma - a cancer that causes increases in circulating catecholamines, so blood pressure goes up radically. Phenoxybenzamine works to bring the BP back down to normal. |
| In general, what are alpha 1 antagonists used in the treatment of? | hypertension and BPH (urinary retention) |
| What is Yohimbine used in the treatment of? | sexual dysfunction disorders (as an alpha 2 antagonist it has dangerous side effects like elevated BP) |
| If you block the Beta 1 receptor, what would you expect to happen? | Decreased heart rate & reduce the work of the heart |
| What is the half life of esmolol? | 10 minutes |
| What is the half life of propanolol? | 3.5 - 6 hours |