Save
Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Anti-hypertensives

Anti-hypertensive drugs

ClassDrugsMechanismAdverse effectsIndications
ACE Inhibitors Captopril (non-peptide - good oral bioavailability), Enalapril Inhibit breakdown of Angiotensin I to II, also inhibit breakdown of bradykinin (vasodilator) - inhibits aldo release and vasoconstriction Reversible renal failure, loss of taste, angiedema (swelling of face and neck), dry nonproductive cough, rash, fetal malformations HTN, MI, Diabetes, Renal insufficiency
ARB Losartan, valsartan block AT1 receptors, decreases PVR - venous side decreases preload, arterial side decreases afterload (decreases LV hypertrophy) - E-3174 carboxylic acid is active metabolite Hyperkalemia, dizziness, fetal injury/death, HTN - stroke prevention, CHF, chronic kidney disease
Vasodilators-CCB Verapamil angina - coronary artery relaxation, peripheral relaxation (decreased afterload). Arrythmias - slow conduction through AV node, decreases HR and contractility. HTN - reduces Constipation, AV block - don't give to those with cardiac conduction problems, and those on alpha blockers
Vasodilators-CCB diltiazem Like verapamil but weaker in everything except coronary artery dilation same as verapamil, but less severe. Gingival sensitivity (blank)
Vasotilators-CCB-dihydropyridines Nifedipine Angina - coronary artery dilation, decrease PVR slight increase in HR (reflex tachycardia) (blank)
Vasodilators-ATP sensitive K+ channels HCTZ, minoxidil, diazoxide, pinacidil (blank) (blank) (blank)
Vasodilators-others nitrates, NaNitroprusside, nitroglycerin activation of guanylyl cyclase excessive vasodilation and hypotension (blank)
Vasodilators - others hydralazine arterial vasodilation reflex tachycardia -lupus like symptoms (blank)
Vasodilators - dopamine agonists fenoldopam very quick acting DA agonist hypokalemia (reflex tachycardia isn't a problem because these patients are usually on IV drip IV drip - short duration in hospital for malignant HTN, or end organ failure (kidney sparing - dilation of both afferent and efferent arteriole)
Sympatholytics-centrally acting Clonidine Alpha 2 agonist (decreases sympathetic outflow to the heart) - can be used as a patch Rebound hypertension if they forget to take their medicine Detox - Opioid withdrawal
Created by: milletbrock
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards