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ccctc test 6 hormone
defenitions for test 6 hormones
| Question | Answer |
|---|---|
| synthesized in various tissue types, released and act locally, exert profound changes in the body | local hormones |
| produced by one specific tissue (gland), act throughout the body, and have a regulatory effect | systemic hormones |
| local hormone found in all tissues of the body, causes bronchial constriction, stomach acid secretion, blood vessel dilation, local edema, pain, and itching | histamine |
| group of local hormones that cause a variety of local reactions such as urterine and bronchial contractions and relaxation, decreased gastric secretions, pain and inflammation | prostaglandins |
| Used in the treatment of allergies, rashes, hay fever, motion sickness, nausea, dizziness. the H2 antagonist is used to treat ulcers and reflux disease | anti-histamines (histamine antagonist) |
| What is the mechanism of action and side effects of anti-histamines? | mechanism of action--inhibits the action of histamine; side effects--drowsiness, CNS suppression, anti-cholinergic effects |
| What are the 3 types of anti-histamines we learned: | Sedating Antihistamines (type 1), Non-sedating Antihistamines (type 1), and Antihistamine (type 2) |
| used to protect the brain internally like the skull is used for protecting it externally | blood brain barrier |
| type 1: competitively antagonize histamine at the H1 receptor (block histamine). They cross the blood brain barrier making them a CNS drug. | Sedating Antihistamine |
| Dyphenhydramine | Benadryl |
| Chlorpheniramine | Chlor-Trimeton |
| Hydroxyzine | Atarax,Vistaril |
| Meclizine | Antivert |
| Promethazine | Phenergan |
| Prochlorperazine | Compazine |
| Type 1--do not cross blood brain barrier, no sedation | non-sedating Antihistamines |
| Loratadine | Claritin |
| Fexofenadine | Allegra |
| Cetirizine | Zyrtec |
| What does the D in Allegra D and Claritin D stand for? | decongestant |
| may cause heart palpitations, tends to increase blood pressure, generic for Sudafed | pseudoephedrine |
| Type 2--competitive blockers of histamine at the H2 receptors, those in the stomach used to treat ulcers and reflux disease and heartburn. | Antihistamine |
| Cimetidine | Tagamet |
| Ranitidine | Zantac |
| Famotidine | Pepcid |
| Nizatidine | Axid |
| These groups of drugs are not H2 receptor antagonists and are not antihistamines. their main action is a long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available today. | proton pump inhibitors (PPIs) |
| what are the uses of proton pump inhibitors (ppis) | dyspepsia, peptic ulcer disease (PUD0, gastroesophageal reflux disease (GERD/GORD), prevention or stress gastritis |
| what is the mechanism of action for PPIs | act by blocking the enzyme system of the gastric cells that secrete gastric acid. |
| What are the side effects of PPIs | headache, nausea, diarrhea, abdominal pain, dizziness |
| Omeprazole | Prilosec |
| Lansoprazole | Prevacid |
| Dexlansoprazole | Kapidex |