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Stack #119779
Parts of the Nephron
| Location | Characteristics |
|---|---|
| Proximal tubual | • simple cuboidal • brush border: large, plentiful microvilli; enormous SA • key: high water permeability, high solute permeability • all organic substances reabsorbed, secreted here • 67% Na+ reabsorbed • 67% H2O reabsorbed |
| thin descending loop of Henle | • simple squamous • no microvilli • key: high water permeability; impermeable to solutes • 10% H2O reabsorbed |
| thick ascending loop/early distal tubual | • cuboidal • smaller, less numerous microvilli • glycoprotein layer in luminal membrane • key: low water permeability; high solute permeability • 25% Na+ reabsorbed |
| late DCT, cortical collecting duct | • cuboidal • key: o intercalated cells: secrete H+ to maintain acid/base balance o principal cells: hormonally regulated permeability to H2O/solutes • 5% Na+ reabsorbed variably |
| medullary collecting duct | • Mainly cuboidal principal cells • key: hormonally regulated permeability to H2O/solutes • 4~5% Na+ reabsorbed variably • 25% remaining H2O may/not be reabsorbed; hormonally regulated |