click below
click below
Normal Size Small Size show me how
Pharm Pretest 2
Term | Classification/MOA | Uses | Adv effects etc |
---|---|---|---|
Conventional (Neuroleptic) Antipsychotic agents | Neuroleptic= "cut of bad neurons" Block DA receptors- NONSELECTIVE Have "positive" adverse effects- above normal function (delusions, hallucinations) | ||
Atypical antipsychotic agents | Moderate blockages of DA receptors; other MOAs Have "positive" and "negative" effects- delusion/hallucination or dull/blunted affect | ||
Chlorpromazine (Thorazine) | Conventional antipsychotic agent- Low potency MOA: block DA, ACh, Histamine, NE receptors | ||
Extrapyramidal Symptoms (EPS) | Acute dystonia- Spasms=> respiratory danger, may require tracheostomy Parkinsonism- block DA too much=> tremors, rigor Akathisea- extreme restlesness Tardive dyskinesia- may be irreversible | ||
CGRP | Calcitonin Gene Related Peptide Related to migraines Plasma levels of CGRP rise during migraines Stimulates trigeminal path => vasodilation, which stretches pain receptors | ||
Antipsychotic agents | 2 Classes: Conventional (Neuroleptic |