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Pharm Pretest 2

TermClassification/MOAUsesAdv effects etc
Conventional (Neuroleptic) Antipsychotic agents Neuroleptic= "cut of bad neurons" Block DA receptors- NONSELECTIVE Have "positive" adverse effects- above normal function (delusions, hallucinations)
Atypical antipsychotic agents Moderate blockages of DA receptors; other MOAs Have "positive" and "negative" effects- delusion/hallucination or dull/blunted affect
Chlorpromazine (Thorazine) Conventional antipsychotic agent- Low potency MOA: block DA, ACh, Histamine, NE receptors
Extrapyramidal Symptoms (EPS) Acute dystonia- Spasms=> respiratory danger, may require tracheostomy Parkinsonism- block DA too much=> tremors, rigor Akathisea- extreme restlesness Tardive dyskinesia- may be irreversible
CGRP Calcitonin Gene Related Peptide Related to migraines Plasma levels of CGRP rise during migraines Stimulates trigeminal path => vasodilation, which stretches pain receptors
Antipsychotic agents 2 Classes: Conventional (Neuroleptic
Created by: mddyob14



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