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51-100 Spring 08
Includes brand name, generic name/therapeutic class, and mechanism of action
| Brand Name | Generic Name | Mechanism of Action |
|---|---|---|
| Keflex | cephalexin/ antibiotic | cephalosporin: inhibits cell wall synthesis |
| Paxil | paroxetine/ anti-depressant | SSRI |
| Reglan | metoclopramide/ anti-emetic | anti-emetic: inhibits DA receptors, which increases vomiting threshold GI motility stimulant: cholinergic activity becomes greater than that of dopamine, which increases smooth muscle response to ACh(Acetylcholine) and causes GI motility |
| Cardizem | diltiazem/ calcium channel blocker | Non-DHP calcium channel blocker |
| Ambien | zolpidem/ hyonotic | agonist of benzodiazepine gamma-aminobutyric acid (GABA-A) subunit |
| Celexa | citalopram/ antidepressant | SSRI |
| Advair | fluticasone & salmeterol/ antiasthmatic | fluticasone: inhibits phospholipase, prostaglandins, and leukotrienes salmeterol: beta-2 receptor agonist |
| Zestoretic, Prinzide | lisinopril & hydrochlorothiazide/ antihypertensive | lisinopril: ACE-I HCTZ: loop diuretic |
| Vytorin | simvastatin & ezetimibe/ antihyperlipidemic | simvastatin: HMG-CoA reductase inhibitor ezetimibe: cholesterol absorption inhibitor |
| Zyrtec | cetirizine/ antihistamine | H-1 receptor antagonist |
| Fioricet | APAP, butalbital & caffeine/ analgesic | butalbital: causes sensory depression by inhibiting conduction in areas of the brain caffeine: stimulates CNS by increasing levels of cAMP |
| Diflucan | fluconazole/ antifungal | inhibits fungal steroid production |
| Ortho-Tricyclen | norgestimate & ethinyl estradiol/ oral contraceptive | norgestimate: progesterone receptor agonist EE: estrogen receptor agonist |
| Depakote | divalproex/ antiepileptic & antipsychotic | MOA unknown (may increase brain GABA levels) |
| Adderall | amphetamine & dextroamphetamine/ CNS stimulant | sympathetic amine with effects similar to epinephrine |
| Celebrex | celecoxib/ NSAID | Cyclo-oxygenase 2 inhibitor |
| Diovan | valsartan/ AT2 antagonist | angiotension-2 receptor blocker |
| Lotrel | amlodipine & benazepril/ antihypertensive | amlodipine: DHP calcium channel blocker benazepril: ACE-I |
| Allegra | fexofenadine/ antihistamine | H-1 receptor antagonist and inhibits histamine release |
| Klonopin | clonazepam/ antiepileptic | benzodiazepine: believed to enhance GABA activity |
| Augmentin | amoxicillin & clavulanate/ antibiotic | clavulanate(clavulanic acid): beta-lactamase inhibitor, which increases the antibacterial activity of beta-lactam antibiotics |
| Cymbalta | duloxetine/ antidepressant | SSNRI: selective seratonin and norepinephrine reuptake inhibitor |
| Risperdal | risperidone/ antipsychotic | MOA unknown (affects serotonin and DA receptors |
| Levaquin | levofloxacin/ antibiotic | Quinolone antibiotic: inhibits bacterial DNA synthesis |
| Aldactone | spironolactone/ diuretic | aldosterone antagonist at the distal convoluted renal tubule |
| Lyrica | pregabalin/ anticonvulsant | MOA unknown (may bind to alpha-2 delta receptors in the CNS |
| Zyloprim | allopurinol/ agent for gout | xanthine oxidase inhibitor, which decreases uric acid production |
| Protonix | pantoprazole/ antisecretory | PPI |
| Actos | pioglitazone/ antidiabetic | peroxisome proliferator-activated receptor (PPAR) gamma agonist |
| Dilantin Kapseals | extended phenytoin/ antiepileptic | enhances neuronal sodium efflux |
| Kenalog | triamcinolone acetonide topical/ corticosteroid | inhibits phospholipase, prostaglandins, and leukotrienes |
| Motrin | ibuprofen/ NSAID | inhibits prostaglandin synthesis |
| Altace | ramipril/ ACE-I | ACE-I |
| Coreg | carvedilol/ beta blocker | non-selective beta blocker (blocks B-1, B-2, and alpha-1 receptors) |
| Verelan | verapamil/ calcium channel blocker | non-DHP calcium channel blocker |
| Estrace | estradiol/ estrogen | estrogen receptor agonist |
| Catapres | clonidine/ antihypertensive | alpha-2 receptor agonist |
| Soma | carisoprodol/ muscle relaxant | MOA unknown (works centrally to produce muscle relaxation) |
| Zetia | ezetimibe/ antihyperlipidemic | cholesterol absorption inhibitor |
| Amaryl | glimepiride/ antidiabetic | sulfonylurea: increases pancreatic insulin release |
| Flomax | tamsulosin/ treats BPH | alpha-1 receptor antagonist |
| Diovan-HCT | valsartan & hydrocholorothiazide/ AT2 antagonist | valsartan: angiotensin receptor-2 blocker HCTZ: diuretic |
| Humalog | insulin lispro/ antidiabetic | binds to insulin receptor (ultra short-acting insulin) |
| Flonase | fluticasone/ nasal decongestant | inhibits phospholipase, prostaglandins, and leukotrienes |
| Tylenol w/ Codeine | APAP & codeine phosphate/ analgesic | same as hydocodone |
| Aricept | donepezil/ antipsychotic | acetylcholinesterase inhibitor (Ach-I) |
| Mevacor | lovastatin/ antihyperlipidemic | HMG-CoA reductase inhibitor |
| Accupril | quinapril/ ACE-I | ACE-I |
| Miralax | polyethylene glycol (PEG) 3350/ laxative | osmotic agent (causes water to be retained in the stool) |
| MS Contin | morphine sulfate/ analgesic | opioid receptor agonist |