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Resp 15

Aerosol Medication Definitions

Aerosol suspension of solid or liquid particles in gas
Goals of aerosol *drugs delivered directly to site of action * Therapeutic action with minimal side effects * Greater efficacy and safety
MDI Metered dose inhaler
DPI Dry powder inhaler
SVN Small volume nebulizer
USN ultrasonic nebulizer
hand-bulb atomizer nose spray
vibrating mesh nebulizer like the USN ultrasonic nebulizer
Jet Nebulizer gas powered directed through a restricted orifice (the jet) - incorporates baffles to decrease the number of large aerosol particles
Peak flow a small, hand held device used to monitor a person's ability to breath OUT
Spacer simple valueless extension
Chamber incorporates a valve resulting in higher resirable drug dosage (will have musical note if you breath to fast)
LVN Large volume nebulizer
SPAG Small particle aerosol generator
instability tendancy for particles to be removed from suspension
penetration refers to the maximum depth that suspended particles can be carried into the pulmonary tree by inhaled tidal air
deposition result of an aerosol's eventual instability; particles "fall out" on a nearby surface
Retention proportion of particles deposited within the respiratory tract
clearance removal, the fact that some particles are exhaled
coalescene two particles form one larger particle
nebulizer a device that generates aerosol of uniform size
gravity large particles are deposited before smaller particles
physical nature of particle some particles absorb water, become large and rain-out, while others evaporate, become smaller and are conducted further into respiratory tree.
Hygroscopic particles tend to absorb water from the resp tract, and become larger and rain out
Hypertonic particles add water, increase size, and decrease deposition to smaller airways
hypotonic particles lose water and increase deposition to small airways
isotonic solutions will remain fairly stable in size until they are deposited
For maximal deposition slow deep breath, inhale through an open mouth, end inspiration, pause, follow with a slow, complete exhaustion
Created by: TnJFarrington12