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Oncology Med
Cancer med
Question | Answer | |
---|---|---|
Temodar | Temozolomide | Alkylators |
Casodex | Bicalutamide | Antiandrogens at the receptor site |
Eulexin | Flutamide | Antiandrogens at the receptor site |
Zoladex | Goserelin | LHRH agonist |
Lupron | Leuprolide | LHRH agonist |
Arimidex | Anastrozole | Aromatase Inhibitors |
Aromasin | Exemstane | Aromatase Inhibitors |
Femara | Letrozole | Aromatase Inhibitors |
Faslodex | Fulvestrant | SERMs |
Evista | Raloxifene | SERMs |
Nolvadex | Tamoxifen | SERMs |
Adriamycin | Doxorubicin | Anthracyclines |
Ellence | Epirubicin | Anthracyclines |
Novantrone | Mitoxantrone | Anthracyclines |
Trexall | Methotrexate | Folate Antimetabolites |
Mexate | Methotrexate | Folate Antimetabolites |
Folex | Methotrexate | Folate Antimetabolites |
Revlimid | Lenalidomide | Decrease angiogenesis |
Talomid | Thalidoide | Decrease angiogenesis |
Avastin | Bevacizumab | Angiogenesis Inhibitor: Limit tumor's blood supply by binding to VEGF-A |
Campath | Alemtuzumab | Cell Surface Marker Target: Targe Lymphocyte CD-52 |
Mylotarg | Gemtuzumab | Cell Surface Marker Target: Targe Leukocytes CD-33 and release Calicheamicin |
Rituxan | Rituximab | Cell Surface Marker Target: Targe Lymphocyte CD-20 |
Bexxar | Tositumomab | Cell Surface Marker Target: Targe Lymphocyte CD-20 and radiolabeled |
Erbitux | Cetuximab | Target Over Expression |
Herceptin | Trastuzumab | |
Afinitor | Averolimus | MTOR Inhibitor |
Paraplatin-AQ | Carboplatin | Platinum Based Compounds |
Platinol | Cisplatin | Platinum Based Compounds |
Eloxatin | Oxaliplatin | Platinum Based Compounds |
Imuran | Azathioprine | Purine Analog Antimetabolites |
Purinethol | Mercaptopurine | Purine Analog Antimetabolites |
6-MP | Mercaptopurine | Purine Analog Antimetabolites |
Xeloda | Capectable | Pyrimidine Analog Antimetabolites |
5-FU | Fluorouracil | Pyrimidine Analog Antimetabolites |
Adrucil | Fluorouracil | Pyrimidine Analog Antimetabolites |
FUDR | Floxuridine | Pyrimidine Analog Antimetabolites |
Gemzar | Gemcitabine | Pyrimidine Analog Antimetabolites |
Taxotere | Docetaxel | Taxanes |
Taxol | Paclitaxel | Taxanes |
Camptosar | Irinotecan | Topoisomerase I Inhibitor |
VePesid | Etoposide | Topoisomerase II Inhibitor |
VP-16 | Etoposide | Topoisomerase II Inhibitor |
Xalkori | Crizotinib | TKIs Target Anaploastic Lymphoma Kinase (ALK) |
Gleevec | Imatinib | TKIs Target BCR-ABL |
Tarceva | Erlotinib | TKIs Target EGFR |
Velban | Vinblastine | Vinca alkaloids |
Vincasar | Vincristine | Vinca alkaloids |
Navelbine | Vinorelbine | Vinca alkaloids |
Trisenox | Arsenic Trioxide | Induces terminal differentiation of cells or apoptosis |
Blenoxane | Bleomycin | Intercalcatine agent blocking topoisomerase II |
Colorectal cancer with K-ras mutation does not respond to this med | Brand: Erbitux Generic: Cetuximab | MOA target over expression of growth factor that promote cancer cell |
Not recommended in lung or liver transplant pt (BBW) | Rapamune | Sirolimus mTOR Kinase inhibitor which inhibit T cell activation and proliferation |
Afinitor | Everolimus | PO Daily with or without food |
Neuropathy exacerbation by exposure to cold | Eloxatin | Oxaliptin |
Testing for TPMP and ITPA deficiency required before starting Tx | Brand: Purinethol Generic: Mercaptopurine | MOA Purine analog that inhibit the synthesis of purine |
Xanthine oxidase inhibitor can raise Bioavailability by 400% - 500%. Required dose reduction when used together | Purinethol | Mercaptopurine PO 1 hr before 2 hr after meal |
Testing for Dihydropyrimidine dehydrogenase (DPD) deficiency. DPD deficiency increase risk of toxicity | Brand: Xeloda Generic: Capecitabine Prodrug of 5FU (Adrucil) | Pyrimidine analog that inhibit pyrimidine synthesis |
Given visa intra-hepatic artery or portal vein infusion for isolated hepatic metastases. Less than 10% reaches systemic circulation fso less toxicity with more of a targeted effect on the metastases | Brand: FUDR Generic: Gloxuridine | Pyrimidine analog antimetabolite |
Hypersensitivity rxn (78%) due to polytoxyethylated castor oil solvent system. Pre-treat with dexamethasone, dephenhydramine and H2-blockers. | Brand: Taxol Generic: Paclitaxel | Brand: Abraxane Paclitaxel albumin bound less hypersensitivity rxns, does not require pre-medication |
Cytoxan | Cyclophosphamide | Alkylators |
Ifex | Ifosfamide | Alkylators |