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1-50 Spring 08

Includes Brand Name, Generic Name/Therapuetic Class, Mechanism of Action

Brand NameGeneric Name/Therapuetic ClassMechanism of Action
Lortab hydrocodone and APAP/ Narcotic Analgesic hydrocodone: opiod receptor agonist acetaminophen: analgesic effect unknown, affects hypothalamic heat regulating center (antipyretic)
Synthroid levothyroxine/ thyroid hormone levothyroxine (T4) replacement
Xanax alprazolam/ antianxiety benzodiazepine: binds to receptors in the central nervous system (CNS)
Micro-K, K-Dur, Klor-Con potassium chloride/ potassium supplement potassium supplement
Glucophage metformin hydrochloride/ antidiabetic main effect believed to be inhibition of hepatic gluconeogenesis (multiple MOAs suspected)
Zestril, Prinivil lisinopril/ ace inhibitor ACE-I (angiotensin converting enzyme inhibitor)
Ultram tramadol/ analgesic binds to opioid receptor, and also inhibits reuptake of norepinephrine(NE) and seratonin (5-HT)
Lasix furosemide/ diuretic "loop diuretic": blocks sodium and chloride reabsorption from kidney tubules
Lipitor atorvastatin/ antihyperlipidemic inhibits 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) and increases hepatic low-density lipoprotein (LDL) receptors
Percocet oxycodone and APAP/ narcotic analgesic oxycodone: opioid receptor agonist acetaminophen: analgesic effect unknown; affects hypothalamic heat regulating center (antipyretic)
Tenormin atenolol/ beta blocker beta-1 receptor antagonist
Toprol XL metoprolol succinate/ beta blocker beta-1 selective receptor antagonist
Lopressor metoprolol tartrate/ beta blocker beta-1 receptor antagonist
HydroDiuril hydrochlorothiazide/ diuretic Diuretic effect: blocks reabsorption of sodium and chloride from renal tubules Antihypertensive effect unknown
Coumadin warfarin/ anticoagulant inhibits vitamin K dependent clotting factors
Norvasc amlodipine/ calcium channel blocker dihydropyridine calcium channel blocker
Amoxil amoxicillin/ antibiotic beta lactam antibiotic; inhibits cell wall synthesis of mucopeptide
OxyContin oxycodone/ narcotic analgesic opioid receptor agonist
Zithromax azithromycin/ antibiotic macrolide antibiotic; inhibits microbial protein synthesis
Darvocet propoxyphene and APAP/ narcotic analgesic propoxyphene: binds to opioid receptor (like codeine, hydrocodone)
Zoloft sertraline/ antidepressant selective seratonin reuptake inhibitor (SSRI)
Zantac ranitidine/ H2 antihistamine Histamine-2 receptor antagonist
Zocor simvastatin/ antihyperlipidemic inhibits HMG-CoA and increases hepatic LDL receptors
Lexapro escitalopram/ antidepressant SSRI
Nexium esomeprazole/ antisecretory proton pump inhibitor (PPI)
Seroquel quetiapine/ antipsychotic Serotonin(5HT), dopamine(DA), histamine and alpha receptor blockers
Proventil albuterol/ antiasthmatic/bronchodilator beta-2 selective receptor agonist
Singulair montelukast/ antiasthmatic Leukotriene receptor antagonist
Plavix clopidogrel/ platelet inhibitor adenosine diphosphate(ADP) receptor antagonist
Deltasone prednisone/ steroid/anti-inflammatory inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
Effexor venlafaxine/ antidepressant potentiates activity of serotonin, norepinephrine, and dopamine
Elavil amitriptyline/ antidepressant increases 5HT and NE levels (prevents reuptake)
Ativan lorazepam/ antianxiety benzodiazepine: binds to receptors in the CNS
Neurontin gabapentin/ antiepileptic MOA unknown
Glucotrol glipizide/ antidiabetic Sulfonylurea: increases pancreatic insulin secretion
Naprosyn naproxen/ NSAID inhibits prostaglandin synthesis
Wellbutrin bupropion/ antidepressant inhibits DA and NE uptake
Desyrel trazodone/ antidepressant MOA unknown; believed to increase serotonin levels
Prilosec omeprazole/ antisecretory PPI
Dyazide triamterene and HCTZ/ diuretic Triamterene: inhibits the reabsorption of sodium in exchange for potassium and hydrogen ions in the renal tubule
Flexeril cyclobenzaprine/ muscle relaxant reduces motor activity in the brainstem
Duragesic fentanyl transdermal system/ narcotic analgesic opioid receptor agonist
Prozac fluoxetine/ antidepressant SSRI
Fosamax alendronate/ osteoporosis agent osteoclast inhibitor
Vasotec enalapil/ ace inhibitor ACE-I
Prevacid lansoprazole/ antisecretory PPI
Lantus insulin glargine/ antidiabetic binds to insulin receptor (24 hour insulin)
Prempro conjugated estrogens and medroxyprogesterone acetate/ estrogen/progestin combination hormone estrogen and progesterone receptor agonists, respectively
Lanoxin digoxin/ cardiovascular inhibits sodium-potassium ATPase
Valium diazepam/ antianxiety Benzodiazepine(BZD): same as Xanax
Created by: ashley3185
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