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MCV2010 Resp drugs
| Respiratory Drug | MOA/ other info |
|---|---|
| Albuterol | selective b2 agonist |
| Epinephrine | non-selective beta agonist (and alpha) |
| Salmeterol | long acting selective b2 agonist |
| Formoterol | slower onset, long acting b2 agonist |
| Ipatropium | anti-cholinergic |
| Tiotropium | long acting anti-cholinergic |
| Theophylline | PDE inhibitors and adenosine receptor inhibitors. |
| Theophylline SE | CNS/cardiac stimulation, vasodilation. |
| Theophylline dec Clearance | dec CL w/ fluoroquinolones, cimetidine, erythromycin |
| Theophylline inc Clearance | inc CL w/ phenytoin |
| Cromolyn | stabilize mast cell membrane, used prophylactically |
| Triamcinolone | inhaled corticosteroid, prophylaxis |
| Budesonide | inhaled corticosteroid, prophylaxis |
| Fluticasone | inhaled corticosteroid, prophylaxis |
| Omalizumab | monoclonal antibody for IgE |
| n-Acetylcysteine | decreases viscosity of pulmonary secretions(also tylenol tox) |
| Codeine | narcotic,centrally active anti-tussive (inc threshold of cough stimul) |
| Hyrdocodone | narcotic,centrally active antitussive(inc threshold of cough stimul) |
| Dextromethorphan | centrally active anti-tussive(raises threshold for cough stim) |
| Guaifenesin | periph acting. expectorant increases outflow of resp.tract fluid |
| Phenylpropanolamine | oral sympathomimetic decongestant |
| Pseudoephedrine | oral sympathomimetic decongestant |
| Sympathomimetic SE | caution for: HT, Cardiac disease, hyperthyroid, diabetes |
| Phenylephrine | topical sympathomimetic decongestant |
| Oxymetazoline | topical sympathomimetic decongestant |
| Diphenhydramine | 1st gen oral anti H1 histamine receptor. no good for asthma. |
| Fexofenadine | 2nd gen oral anti H1 histamine receptor. no good for asthma. |
| loratadine | 2nd gen oral anti H1 histamine receptor. no good for asthma. |
| Colfosceril | synthetic pulm. surfactant for premature infants with RDS |
| Dornase Alfa | for CF. human DNAase enzyme by inhalation breaks down mucus plug |