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Immune Drug
Use of Drugs in Treatment of the Immune System
| Question | Answer |
|---|---|
| Cyclosporine | immunosuppression for organ transplant, tear production (Restasis)tear production suppressed by ocular inflammation |
| Restasis | Cyclosporine used for tear production suppressed by occular inflammation |
| Tacrolimus (Prograf) | organ transplant, eczema, atoptic dermatitis |
| Mycophenolate Mofetil (CellCept) | solid organ transplant, rheumatoid arthritis, psoriasis, systemic lupus, inflammatory bowel disease |
| Hydroxychloroquine (Plaquenil) | rheumatoid arthritis, systemic lupus erythematosus |
| Adalimumab (Humira) | rheumatoid arthritis (symptoms and disease progression), Crohn’s disease, plague psoriasis |
| Abatacept (Orencia) | rheumatoid arthritis, juvenile rheumatoid arthritis |
| Alefacept (Amevive) | plaque psoriasis (majority of psoriatic lesions have CD4 and CD8 cells which up regulate CD2 on surface) |
| Basiliximab (Simulect) | renal transplant patients, off label liver transplant |
| misprostol | ulcer protection |
| riopoprostil | ulcer protection |
| enprosil | ulcer protection |
| Dinoprostone (synthetic PGE2) | cervical gel used in cervical ripening, induction of labor and therapeutic abortion |
| Misoprostol (PGE1) Combined with mifepristone (progestin antagonist) | abortifacient |
| NSAIDs affect during pregnancy | NSAIDs can prolong pregnancy and inhibit labor |
| alprostadil (natural PGE1) | used to maintain shunt in infants with congenital heart defects |
| Indomethacin | closure of shunt in infants with congenital heart defects |
| epoprostenol (PGI2) (Flolan) | primary pulmonary HTN, inhibit platelet aggregation when heparin is contraindicated |
| Zafirlukast | LT receptor antagonists; effective prophylaxis in asthma; variable responsiveness |
| montelukast | LT receptor antagonists; effective prophylaxis in asthma; variable responsiveness |
| Zileuton | 5-lipoxygenase inhibitor |
| Latanaprost (Xalantan) | treatment of open angle glaucoma (more effective than timolol) |
| travoprost (Travatan) | treatment of open angle glaucoma (more effective than timolol) |
| Misoprostol (PGE analogue) | termination of pregnancy, prevent NSAID associated ulcers |
| Aspirin | antipyretic, analgesia, anti-inflammatory, inhibition of platelet aggregation and thrombosis, premature labor |
| NSAIDs | antipyretic, analgesia, anti-inflammatory, |
| Acetaminophen | antipyretic, analgesia |
| Indomethacin* (sulindac; etodolac) | Antiinflammatory, analgesic, antipyretic. (Rheumatic conditions, Patent ductus arteriosus, Inhibition of premature labor) |
| Ibuprofen*, (naproxen, fenoprofen ketoprofen) | antipyretic, analgesia, anti-inflammatory, |
| Allopurinol | long term (NOT acute- don't use during attakcs) treatment of gout |
| Probenecid*; sulfinpyrazone | gout |
| Colchicine | relief of acute gout attacks, sometimes used long term but not as good as allopurinol |
| Febuoxstat (Uloric) | treatment of gout |
| Diphenhydramine (Benadryl) | H1 receptor antagonist |
| Chlorpheniramine (Chlor-Trimeton) | H1 receptor antagonist |
| Brompheniramine (Dimetapp) | H1 receptor antagonist |
| Clemastine (Travist) | H1 receptor antagonist |
| Loatidine | H1 receptor antagonist |
| Cetirizine | H1 receptor antagonist |
| Fexofenidine | H1 receptor antagonist |
| Desloratadine | H1 receptor antagonist |
| Meclizine | H1 receptor antagonist, motion sickness |
| Dimenhydrinate | H1 receptor antagonist, motion sickness |
| Promethazine | H1 receptor antagonist, emesis |
| cimetidine (Tagamet) | H2 antagonists, inhibit acid production |
| ranitidine (Zantac) | H2 antagonists, inhibit acid production |
| famotidine (Pepcid) | H2 antagonists, inhibit acid production |
| nizatidine (Axid) | H2 antagonists, inhibit acid production |
| sumatriptan | migraine treatment, the "triptan" class |
| naratriptan | migraine treatment, the "triptan" class |
| eletriptan | migraine treatment, the "triptan" class |
| zolmitriptan | migraine treatment, the "triptan" class |
| ondansetron | antagonists at 5-HT3 receptors, emesis |
| granisetron | antagonists at 5-HT3 receptors, emesis |
| butanopride | antagonists at 5-HT3 receptors, emesis |
| zacopride | antagonists at 5-HT3 receptors, emesis |
| Cyproheptadine | (5-HT1Aantagonist)also blocks histamine (H1)receptors Used for skin allergies; GI hypermotility etc. |
| Ketanserin | (5-HT2 & 5-HT2C) antagonists also blocks a1adrenergic receptors; reduces platelet aggregation and blood pressure |
| buspirone | (5-HT1A agonists):- antianxiety |
Created by:
Kachmiel
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