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Eicosanoids.,

Pharmacology Immune System

QuestionAnswer
Prostaglandins Large family of structurally similar compounds with specific biological actions, Share a chemical structure (prostanoid)
PG1 (derived from...) dihomo-y-linolenic acid (DHGLA) & eicosatrienoic acid
PG2 (derived from...) Most prevalent direct derivative of arachidonic acid
PG3 (derived from...) Derived from eicosapentaenoic aicd (EPA)
PGE1 (primary biological effects...) vasodilation, decreased gastric acid secretion, bronchodilation
PGE2 (primary biological effects...) vasodilation, decreased gastric acid secretion, pain sensitization, uterine contraction, cervical ripening, aintence of patent ductus arterious, bronchodilation, fever
PGF2alpha (primary biological effects...) bronchoconstriction, uterine contraction, increases drainage from aqueous humor
PGI2 (primary biological effects...) vasodilation, maintence of patent ductus arteriosus, inhibition of platelet aggregation, pain sensitization, gastric cytoprotection
TXA2 (primary biological effects...) Platelet aggregation, bronchoconstriction
LTC4 (primary biological effects...) bronchoconstriction
LTD4 (primary biological effects...) bronchoconstriction
LTE4 (primary biological effects...) bronchoconstriction
LTB4 (primary biological effects...) chemoattraction and activation of polymorphonuclear leukocytes
Created by: Kachmiel
Popular Pharmacology sets

 

 



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