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Pharmokinetics-med
pharmokinetics
| Question | Answer |
|---|---|
| Aqueous solution | a substance dissolved in water adn syrup |
| Aqueous suspension | Solid particles suspended in a liquid |
| Emulsion | Fat or oil suspended in liquid with an emulsifier |
| Elixir | aromatic, sweetened alchohol solution |
| Tincture | Alcohol extract of plant or vegtable substance, commonly used as an antiseptic |
| Capsule | gelatin case that contains liquid, dry or beaded particles |
| Tablet | compressed powdered drug in a small disk |
| Troche | medicated tablets that dissolve slowly |
| Ointment | semisolid mediciine |
| bitransformation | a process in which drugs are chemically converted to metabolites |
| Potentiation | the enhancement of effect caused by concurrent administration of two drugs in which one drug increases the effect of another |
| Summation | the combined effect of two drugs such that the total effect EQUALS the sum of the individual effects of each aget 1+1=2 |
| Synergism | the combined action of 2 drugs effect EXCEEDS the sum of individual effects 1+1=3 |
| Untoward effect | a side effect that proves harmful to the patient |
| Pharmokinetics | The study of how the body handles a drug over a period of time |
| Schedule I drugs | High abuse -heroin, weed,ecstacy |
| Schedule II drugs | High abuse, but accepted medical use- opium,morphine,cocaine |
| Schedule III drugs | less abuse-codeine, hydrocodone, |
| Schedule IV drugs | Low abuse- phenobarbitol, diazepam,lorazepam |
| Schedule V drugs | low abuse-coughs meds, diarrhea meds |
| Erectile disfunction drugs | Cialis,levitra,sildenafil |
| Rectal route | 50% of a drug will not be routed through the liver on the 1st pass |
| SQ injection volume | 0.5-1 ml |
| IM injection volume | 1-5ml |
| Pharmocodynamics | The study of the mechanism of drug action on living tissue |
| Biological half life | the time required to metabolize or eliminate half the total amount of a drug in the body |
| Affinity | attraction between a medication and a receptor |
| IV route is as fast as ... | ET route |
| What drug can be administered intranasally | naloxone, (narcan) |
| Loading Dose | A larger dose of the same concentration and intended to achieve a therapeutic blood level quickly |
| Bioavailability | the amount of drug that is still active when it reaches its target organ |
| Antagonist | has a higher affinity for the receptor site than the chemical mediator |
| Onset of action | The time it takes for the concentration of a medication to reach a minnimum effective level at it's target tissue |
| Half Life | the time nessesary to reduce plasma value to half its initial value |
| Excretion through lungs is affected by... | minute volume and CO |
| Efficacy | ability to cause an expected response |
| Tachyphlaxis | Rapidly occuring tolerance |
| Maintainence dose | amount needed to maintintherapeutic level |
| Teaspoon holds | about 5mls |
| Succinycholine is a Neuromuscular blocking | depolarizing agent` |
| Mydriasis | pupil dilation |
| Side effect | unwanted but predictable reaction |
| Trycillic antidepressants work by | blocking norepinephrine and seretonin from being reabsorbed by the brain |