Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
ch 1and 2 ceutics
kira's notes
| Question | Answer |
|---|---|
| A drug product approved or unapproved by the FDA that produces pharmacological activity | API (active pharmaceutical ingredient) |
| drug with unknown clinical, toxociological, physical, and chemical properties that is unapproved by the FDA | NCE NEW Chemical Entity |
| what drug development phase test on animals for efficacy | preclinical |
| what drug development phase clinical testing on human volunteers for safety only | phase one |
| what drug development phase tests on small batch of patients | phase two |
| what drug development phase does large scale studies on patients with controls | phase three |
| what application is submitted between preclinical and Phase one | IND investigational New Drug |
| what application is submitted after phas 3 of clinical trials-if accepted, drug can be marketed | NDA New Drug Application |
| what is used to extend the patent life and can change the dosage form or strength, not the indication | product line extention (after drug is already on the market) |
| drugs that are marketed under trade name by the pharmaceutical man. | Brand Named Drugs |
| Drugs that are made with same active ingredient and dosage form after patent expires | Generic drugs |
| what four things must be the same when producing a generic drug | therapeutically equivalent, contain same amount of drug, be the same dosage form, and be bioequivalent |
| what does bioequivalent mean | same rate and extent of absorption |
| generic tablets must be the same as there band counter part in all but what 4 things | they may differ in size, color, shape and excipients |
| what application must a manufactor fill out in order to produce a generic drug | and ANDA |
| what two studies must be performed in order for a manufactoring company to produce a generic drug | biequivilance and human toxicology studies only |
| QC or QA ensures the quality of the drug and contents | QC |
| QC or QA controls what is going into your body | QC |
| QC or QA ensures quality of the process and manufacturing site | QA |
| QC or QA ensures that the plant and process are up to par | QA |
| which of the following has greater particle size true solution, colloidal dispersion, or coarse dispersion | coarse dispersion>colloidal>true solution |
| what three properties do colloids exhibit | tyndall, brownian movement, electrophoresis |
| ____is random movement of particles while____ is scattering of light beam and reflection off of particles | brownian movement, tyndall effect |
| uncharged solutes that do not conduct electical current | nonelectrolytes |
| which of the following is not an example of a nonelectrolyte ephedrine, urea, glycerin, sucrose and naphthalene | ephedrine is an electrolyte |
| _have regular colligative properties while ____ do not exhibit colligative propertices | nonelectroytes do electrolyes don't |
| ephedrine and phenobarbital are | electrolytes and not exhibit colligative properties |
| the sum of properties of constituents in solution are ____ properties | additive properties |
| ____properties depend on mode of linkage of the atoms in the molecule | constitutive properties |
| optical rotation is a example of what kind of property | constitutive property |
| which property depends on number of ions dissociated, not mass of ions | colligative properties |
| melting point and freezing point are examples of ____ properties | colligative |
| which properties depend on molecular weight-sum of the masses of constituent atoms | additive properties |
| buffers are compounds that resist changes in pH upon addition of ___ and is usually a combination of ___ and ____ | acid combo of weak acid and conj base or weak base and conj acid |
| the ability of a buffer to resist changes in pH is know as | buffering capacity |
| when buffering capacity is at its best, the ph of a solution should change | very little |
Created by:
lainylaina
Popular Pharmacology sets