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Nitro
| Question | Answer |
|---|---|
| MOA | Relaxes vascualr smooth muscle,promoting vasodilation |
| MOA | Decreases preload-venous dilation |
| MOA | decreases afterload=decreased arteriole pressure=decreased aortic pressior=LV works better |
| MOA | decreases myocardial O2 consumption/workload |
| MOA | Improvescollateral flow to ischemic regions |
| MOA | dilates pulmonary capillary beds-fluid in the alveoli and interstitial spaces are pulled back into the vessels |
| Indiaction | Angina |
| Indication | CP with MI |
| Indication | Pulmonary edema associated with CHF or MI |
| Indication | Hypertensive emergencies with acute coronary syndromes or acute CHF |
| COntra | Increased ICP |
| COntra | Hypotension |
| Contra | hypovolemia |
| Contra | Viagra use withing 24 hrs |
| COntra | Right ventricular MI |
| Contra | severe bradycardia or tachycardia |
| Contra | Hypersensitivity |
| Initial dose | 0.3-0.4 mg tablets every 5 min up to 3 or 1-2 sprays every 5 min up to 3 in 15 minutes |
| CNS SE | Anxiety,confusion,dizzy,headache,weakness |
| Cardio SE | A-fib,Collapse-LT, dysrhythmias-LT,palpitations,postural hypotension,syncope |
| GI SE | abd pain,dyspepsia,n/v |
| GU SE | dysuria,urinary frequency |
| Skin SE | flushing,pallor,sweating |