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Sodium Bicarbonate
sodium bicarb
| Question | Answer |
|---|---|
| MOA | neutralizes excess acid,allows sympathomimetic agents to work more effectively |
| MOA | raises the pH in serum and urine so drugs can be excreted |
| MOA | encourages redistrabution of K+ from extracellular to intracellular-increasesH+ causes K+ to move out and H+ moves into the intracellular space |
| MOA | Electrolyte replacement |
| Indications | Metabolic acidosis |
| Indication | Certain poisonings (methanol/ethylene glycol) |
| Indication | Rhabdomyolosis |
| Indication | Hyperkalemia |
| Indication | Overdoses (barbituates,trycillic antidepressants,ASA,lithium,cocaine,diphenhydramine |
| Indication | DKA |
| Indication | prolonged resucitation with effective ventilation |
| Indication | ROSC after long arrest interval |
| Contra | Hypokalemia/hypocalcemia/hypernatremia |
| Contra | CHF |
| COntra | Metabolic/respiratory alkalosis |
| Contra | Renal failure |
| Contra | Abd pain of unknown origin |
| Contra | HTN |
| Supplied | 50 meQ/50 ml IVP |
| Initial dose | 1meQ/kg IVP repeat in 10 min |
| Sub dose | 0.5 meq/kg IVP |
| CNS SE | confusion,headache,sizures-LT,weakness |
| Cardio SE | cardiac arrest-LT,edema,weight gain, retention |
| Metabolic SE | alkalosis,hypocalcemia, hypokalemia,intracellular acidosis if not ventilated right |
| Resp SE | apnea-LT,induces left shift in oxy-dissocociation curve |