Question
click below
click below
Question
Normal Size Small Size show me how
Digitalis (digoxin)
Digoxin
Question | Answer |
---|---|
Class | Cardiac glycoside |
MOA | Inhibits Na+ K+ pump=increaed Na and Ca in the intracellular space=increased cardiac contractility (+inotropic effect) |
MOA | decreases vagal tone=decreased SA node firing,prolongs conduction through AV=(-chronotropic) |
MOA | In a-fib and A-flutter it decreases the number of atrial impulses(-chronotropic) |
MOA | improves CO (decreases baroreceptor response=decreased SNS discharging=decreased BP due to (+inotropic effects) |
Indications | Controls ventricular rate in A-fib/A-flutter |
Indications | psvt |
Indication | CHF |
Indication | Cardiogenic Shock |
Contra | V-vib/V-tach |
Contra | 2nd and 3rd heart block- in the absence of a parcemaker |
Contra | Digitalis toxicity |
Supplied | 0.25 mg-1mg in 1-2 ml SIVP |
Initial dose | 4-6 mcg/kg over 5 min SIVP |
2nd and 3rd doses | 2-3 mcg/kg |
CNS side effects | Anorexia,confusion,delerium,headache,cns depression,weak |
Cardi SE | a-fib-LT,V-fib/V-tach-LT,AV block-LT, brady,hypo |
Blood SE | thrombocytopenia |
GI SE | diarreah,hemmoraggic necrosis of the intestine,n/v |