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Diltiazem (cartizem)
druginfo
Question | Answer |
---|---|
Class | calcium channel blocker |
MOA | Inhibits calcium influx across a cell membrane during depolarization |
MOA | systemic vasodilation =decreased BP |
MOA | Coronary vasodilation=decreased frequency and severity of attacks of angina |
MOA | Suppression of arrythmias |
MOA | relaxes coronary vascular smooth muscle |
MOA | Slows SA/AV conduction times,dilates peripheral arteries |
Indication | Stable SVT dysrythmias |
Idication | A-fibb and A-flutter with RVR |
Indication | MAT |
COntra | Sick sinus syndrome |
Contra | 2nd/3rd Heart blocks |
COontra | BP<90 mm/Hg |
Contra | recent MI or pulmonary congestion |
Contra | WPW with A-fib or flutter |
Contra | Cardiogenic Shock |
Contra | Use of beta blockers |
Contra | Wide complex tachy |
Contra | Posion or drug induced tachyarrythmias |
How supplied | 25mg/5cc vial or 50 mg/10 ml vial |
Initial dose | 0.25 mg/kg over 2 min |
average ID | 15-20 mg |
Subsequent dose | repeated in 15 mins, 0.35 mg/kg over 2 min |
Average SD | 20-25 mg |
Maintainence dose | 125 mg(25cc)/100 ml |
infuse at | 5-15 mg/hr |
Diltiazem is incompatible with what? | lasix |