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Diltiazem (cartizem)
druginfo
| Question | Answer |
|---|---|
| Class | calcium channel blocker |
| MOA | Inhibits calcium influx across a cell membrane during depolarization |
| MOA | systemic vasodilation =decreased BP |
| MOA | Coronary vasodilation=decreased frequency and severity of attacks of angina |
| MOA | Suppression of arrythmias |
| MOA | relaxes coronary vascular smooth muscle |
| MOA | Slows SA/AV conduction times,dilates peripheral arteries |
| Indication | Stable SVT dysrythmias |
| Idication | A-fibb and A-flutter with RVR |
| Indication | MAT |
| COntra | Sick sinus syndrome |
| Contra | 2nd/3rd Heart blocks |
| COontra | BP<90 mm/Hg |
| Contra | recent MI or pulmonary congestion |
| Contra | WPW with A-fib or flutter |
| Contra | Cardiogenic Shock |
| Contra | Use of beta blockers |
| Contra | Wide complex tachy |
| Contra | Posion or drug induced tachyarrythmias |
| How supplied | 25mg/5cc vial or 50 mg/10 ml vial |
| Initial dose | 0.25 mg/kg over 2 min |
| average ID | 15-20 mg |
| Subsequent dose | repeated in 15 mins, 0.35 mg/kg over 2 min |
| Average SD | 20-25 mg |
| Maintainence dose | 125 mg(25cc)/100 ml |
| infuse at | 5-15 mg/hr |
| Diltiazem is incompatible with what? | lasix |