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Verapimil (isoptin)
drug info
| Question | Answer |
|---|---|
| Class | calcium channel blocker,antidysrythmic,antihypertensive,antianginal |
| MOA | Inhibits movement of calcium during depolarization |
| Decreases afterload due to what? | dilation of arterioles |
| MOA | depresses myocardial contractility |
| MOA | inhibits coronary vasospasm |
| MOA | slows SA and AV node conduction,decreases atrial automaticity, may cause high degree heart blocks |
| MOA | Decreases myocardial O2 requirements |
| Has greater effect on conduction system or smooth muscle? | conduction system |
| Indications | SVT/Junctional tachy-after adenosine |
| Indication | A-fib or A-flutter with RVR |
| Indication | MAT |
| Idication | Angina-prinzemetals,chronic stable and Preinfarction angina |
| Indication | Hypertension |
| Contra | cardiogenic shock |
| COntra | severe CHF |
| COntra | Sick sinus syndrome |
| Contra | Bradycardia |
| Contra | Heart blocks 2nd and 3rd |
| Contra | Severe hypotension |
| Contra | Acute MI |
| Contra | WPW with a-fib o flutter |
| Contra | V-tach-allo wide complex tachycardias |
| Supplied | 5mg/2ml |
| Initial dose | 2.5-5 mg SIVP |
| Subsequent Dose | 5-10 mg SIVP 15-30 minutes after initial dose |
| Total dose | 20 mg |