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Pharm exam 3 MC

atorvastatin (Lipitor) HMG-CoA Reductase Inhibitors single dose, w/meal (afternoon or bedtime), preg x, eat fish
lovastatin (Mevacor) HMG-CoA Reductase Inhibitors -BID
simvastatin (Zocor) HMG-CoA Reductase Inhibitors
pravastatin (Pravachol) HMG-CoA Reductase Inhibitors
fluvastatin (Lescol) HMG-CoA Reductase Inhibitors
cholestyramine (Questran, LoCholest, Prevalite) Bile Acid Sequestering Agents (Antilipemic) -lipids released in feces, combined w/bile prevents absorption
colestipol (Covestid) Bile Acid Sequestering Agents (Antilipemic)
colesevelam (Welchol) Bile Acid Sequestering Agents (Antilipemic) smaller pills given daily
niacin Nicotinic Acid ^HDL, GI s/e flushing (prevent with aspirin), hot flashes, take w/cold water, report joint pain or sclera
Vitamin B3 Nicotinic Acid
gemfibrozil (Lopid) Fibric Acid Derivatives prototype, decreae VDL 50%
clofibrate (Atromid-S) Fibric Acid Derivatives Can cause tumors, more effective on vldl
fenofibrate (Tricor) Fibric Acid Derivatives
ezetimibe (Zetia) Cholesterol Absorption Inhibitor prototype- given with statin
exetimibe & simvastatin (Vytorin) Cholesterol Absorption Inhibitor
nitroglycerine Organic Nitrate Vasodilators relaxes smooth muscle, potent vasodilator, ^periph pooling, decrease afterload, anti HTN, 3x15min or then call 911, tachycard, drops BP, avoid alcohol, keep dry or in glass/original, not with ED drugs (24-48hrs)
isosorbide dinitrate (Sorbitrate, Isodil) Organic Nitrate Vasodilators
isosorbide mononitrate (Imdur) Organic Nitrate Vasodilators
atenolol (Tenormin) Beta Blockers prophylaxis for migraines, placed on inderol first, not for dysrhythmia only for HTN
propanolol (Inderol) Beta Blockers** prototype, decrease dsy, prevents MI, decrease HR and BP S/E- ortho hypo/hyper, decr. libido. Hold if severe dizziness, faingint, bradycardia, dyspnea, or seizures
metoprolol (Lopressor, Toprol-XL) Beta Blockers not for dysrhythmia only for HTN
diltiazem (Cardiazem) Calcium Channel Blockers prototype..s/e- constipation, increases dig level so decrease dig dose
verapamil (Calan, Isoptin) Calcium Channel Blockers prototype cc blocker for dysrhythmias
nifedipine (Adalat, Procardia) Calcium Channel Blockers
nicardipine (Cardene) Calcium Channel Blockers
retaplase (Retavase) Thrombolytics
stretokinase (Streptase, Kabikinase) Thrombolytics
urokinase (Abbokinase) Thrombolytics
altiplase (Activase, TPA) Thrombolytics prototype...dissolves ALL clots...bleeding is severe and hard to stop, CI- ppl with hemorrhage or Hem stroke...half life 20-35 seconds, dedicated line
statins HMG-CoA Reductase Inhibitors
chol Bile Acid Sequestering Agents (Antilipemic)
fibr Fibric Acid Derivatives
nitr Organic Nitrate Vasodilators
olol Beta Blockers
ase Thrombolytics
MONA Morphine Oxygen Nitrate Aspirin Adjunct treatment of MI
quininidine gluconate (Quinaglute) Sodium Channel Blockers Class 1
procainaamide (Pronestyl) Sodium Channel Blockers Class IA prototype, potent neg inotropic, given IM, keep med from light and moisture
lidocaine (Xylocaine) Sodium Channel Blockers Class 1 & 2 (IB) for Vent dysrhy., numbness of lips and tongue, careful abt. strength
phenytoin (Dilantin) Sodium Channel Blockers Class 2 ^ automaticity, fixes digoxin toxicity, monitor LOC
acebutolol (Sectral) Beta Blockers
esmolol (Brevibloc) Beta Blockers
amiodarone (Cordarone) Potassium Channel Blockers prototype, ^prolonged refractory period (AV conduction too), prevents A and V dysrhythmias, S/E- pneumonia like symptoms, blurred vision
digoxin (Lanoxin) Misc Antidysrhythmic & Cardiac Glycosides & Inotropic Agents neg chr and dro, positiv inotropic... see white halos, get apical pulse (hold if <60)
adenoside (Adenocard) Misc Antidysrhythmic convert paroxysmal SVT
hydrochlorothiazide (HCTZ, Hydrodiuril, Esidrix) Thiazide Diuretic
triamterene (Dyrenium) Potassium Sparing Diuretics
chlorothiazide (Diuril) Thiazide Diuretic
furosemide (Lasix) Loop Diuretic proto
ethacrinic acid (Edecrine) Loop Diuretic
bumetanide (Bumex) Loop Diuretic
torsemide (Demadex) Loop Diuretic
triamterene (Dyrenium) Potassium Sparing Diuretics
spironolactone (Aldactone) Potassium Sparing Diuretics
amiloride (Midamor) Potassium Sparing Diuretics
enalapril (Vasotec) ACE inhibitor prototype...decrease sodium and water retention
benzepril (Lotensin) ACE inhibitor
captopril (Capoten) ACE inhibitor
pril ACE inhibitor
doxazosin (Cardura) Alpha 1 Adrenergic Blockers prototype, direct acting on heart, causes vasodilation, dont give with OTC meds (same with any HTN drugs)
prazosin (Minipress) Alpha 1 Adrenergic Blockers
osin Alpha 1 Adrenergic Blockers
clonidine (Catapres) Alpha 2 Adrenergic Blockers
methyldopa (Aldomet) Alpha 2 Adrenergic Blockers
carteolol (Cartrol) Alpha 1 & Beta 2 Blockers Centrally Acting
labetalol (Trandate, Normodyne) Alpha 1 & Beta 2 Blockers Centrally Acting
hydralazine (Apresoline) Direct Vasodilators prototype, ^coronary,renal,and cerebral BF, s/e- orth hypo
nitroprusside (Nitropress, Nipride) Direct Vasodilators DOC HTN emergencies when diast. >120, IV pump, half life 2 secs, rebound htn, blurred vision, delirium, tinnitis, protect from light,
minoxidil (Loniten) Direct Vasodilators
diazoxide (Hyperstat) Direct Vasodilators
lisinopril (Prinivil, Zestril) ACE inhibitor
candesartan (Atacand) ARBs
valsartan (Diovan) ARBs
ARBs Angiotensin II Receptor Blockers
Digoxin immune Fab (Digibind) antidote for Digoxin
carvedilol (Coreg) Beta Adrenergic Blockers
nesiritide (Natrecor) peptide hormone
milrinone (Primacor) Phosphodiesterase Inhibitors
inamrinone Phosphodiesterase Inhibitors
amrinone (Inocor) Phosphodiesterase Inhibitors
normal human serum albumin (Albuminar, Albutein) colloid (large proteins)...prototype
norepinephrine (Levaterenol, Levophed) Vasoconstrictors/Vasopressors/Sympathomimetics DOC for septic shock, S/E- severe HTN and gangrene, blurred vision, photophobias
isoproterenol (Isoprel) Vasoconstrictors/Vasopressors/Sympathomimetics
phenylephrine (Neo-synephrine) Vasoconstrictors/Vasopressors/Sympathomimetics
mephentermine (Wyamine) Vasoconstrictors/Vasopressors/Sympathomimetics
dopamine (Dopastat, Inotropin, Intropin) Inotropic Agents prototype...antidote for Norepenephrine,....LOW,HIGH, AND VERY HIGH DOSES
dobutamine (Dobutrex) Inotropic Agents
phentolamine (Regitine) alpha adrenergic blocker dopamine antidote
epinephrine (Adrenalin) sympathomimetic nonselective adrenergic agonist must have emergency equip on hand, CI, HD, cerepreal atherosclerosis, hyperthyroidism, makes BP worse
heparin sodium (Liquaemin, Calciparine) Anticoagulant prototype...don't give with stable clot, MI, DVT or stroke
enoxaparin (Lovenox) Anticoagulant do not massage (causes bruising), SUBQ (not within 3 inches of another dose)
ardeparin (Normifol) Anticoagulant given with total knee replacement
dalteparin (Fragmin) Anticoagulant
Protamine Sulfate antidote for heparin!! S/E- if adm. too fast, resp difficulties, bradycardia, hypotension, use-combines and deactivates heparin
warfarin sodium (Coumadin) Anticoagulant prototype, interferes w/vitamin k in liver synthesis and clotting factors use- prophylaxis of DVT, PE, Afib, or after MI/CVA/valve replacement...give steady vitamin k foods s/e-bleesing, hives (uriticaria), transient alopecia, preg X,
phytonadione (Mephyton or AquaMephyton) antidote for oral anticoagulant (warfarin) tx and prevent hypoprothrombinemia (esp in newborns!) nsg precautions- increase intake of vitamin k, photosensitivityf
clopidogrel (Plavix) Antiplatelet used for AFIB s/e- tinnitis (ringing in ears), neutropenia nsg resp- w/food (increases absorption and decreases S/E,pt wear medical alert bracelet
aspirin (NSAID) Antiplatelet
ticlopidine (Ticlid) Antiplatelet
dipyridamole (Persantine) Antiplatelet use- after heart surgery, valve replacement, CA bypass
pentoxifylline (Trental) Hemorrheologic Drugs use- PVD for intermittent claudicatoin...decreases blood viscosity and increases blood flexibility (LAZY RIVER DRUG!!)
ace inhibitors potent vasoconstrictor, sodium water retention s/e=neutrapenia**, cough, sex function change, PREG D, take with GF juice
beta blockers S/E-bronchoconstriction, insomnia, decrease av conduction...tapper off...hold if BP 90/60
direct vasodilators priapism, monitor daily weights, tapper off, CI systemic lupuserythematous
calcium channel blockers slows HR, use: htn (decreases pvr), angina, chf, dysrhythmias, SVT*, ^digoxin S/E- constipation!...increase fiber in diet, ovoid sudden position changes, no grapefruit juice!
dong quai herbal, vasodilator, balance effects of estrogen, sedative, and antispasmotic, ^ risk of bleeding
ginger herbal- N/V/GAS/ digestions, antiemetic
ginseng increase gen. well being, acts similar to CC blockers, increase heparin effects and diuretics
thrombolytics bleeding hard to control, destroys all clots, for acute thrombolytic strokes, given Q2 hrs
vasoconstrictors acts directly on AA receptors, raise BP, +ino, tapper
anticoagulants prevents clots from getting bigger...NSG respons.- tell to use soft tooth brush/electiz razor (gum bleeding), avoid constrictive clothes, crossing legs, prolonged bedrest/sitting, and GI upset meds (aspirin and NSAIDS), limit vitamin K rich foods
aPTT monitors HEPARIN pharmacotherapy
PT monitors WARFARIN pharmacotherapy
Symptoms of bleeding echymosis (bruising), petechiae (red spots), hematemesis (vomit in blood), hematuria
garlic decreases platelet aggregation
heparin dosage SUBQ q8-12 hrs IV- loading dose, over 24 hrs 1000 cc NS
vitamin k foods green veggies, liver, dairy
check for bleeding q 15 minx4 hrs.....q30 min x8hrs......q4hrs after
phosphodiasterase inhibitors For HF (not DOC) report fever of over 101 or chest pain
Created by: midnight1854



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