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Stack #1046095

QuestionAnswer
sildenafil (Viagra) 30min onset/4hrs duration
Vardenafil 30min onset/4hrs duration
Tadalafil 45min onset/36hrts duration
cGMP PDE-5 inhibitors PDE5 breaks down cGMP
cGMP highest in_____/[low]_____ in: corpus caverosum/smooth muscle [PDE-5 can cause hypotention=reflex is to incr in <3 rate [CV side effects w/ cardiVdisease]
PDE5 helps w/ color recognition B/G
how is cGMP made? Ach-->M receptor--->NO activates guanylcyclase--->cGMP(vasodilates ↓BP)
Botulinium Toxin prevent ACh release [classic anti-chol/paralysis]
Botulinium Toxin trmts excess sweating, eye disorders, wrinkles [BOTOX]
Anticholingeric [Antimuscarinic] Drugs competitive antagonist at muscarinic receptors
Effects of Antichol/antimusc drying secreatins, ↓tone/motility of GI tract, relax bladder/urine retention, brochodil, mydriasis incr intraocular P, incr <3 rate, CNS: sedation/amnesia @ ↓doses [excitation/seizures @ toxic doses] Quarternary salts don't produce CNS effects-need BBB
Created by: nvan26
Popular Pharmacology sets

 

 



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