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Med management of CA

medical managment of cancer

when a tumor has completely lost identity with the parent tissue, it is considered to be undifferentiated or anaplastic
T/F the more differentiated a tumor becomes, the faster the metastasis and worse the prognosis F
disorganization of cells dysplasia
hyperplasia increase in cell numbers
what is the most advanced form of metaplasia called anaplasia
carcinoma epithelium
glandular adenocarcinoma
CT sarcoma
hematopoetic leukemia and myeloma
viruses are associated with what percent of human cancers 15%
chemicals in tobacco smoke are responsible for what percent of CA 30
exposure to large amounts of x-rays promotes to what CA leukemia
Ann Arbor: Stage 1 local CA in one area and local surrounding area; usually no other systemic or clinical symptoms
Ann Arbor: Stage 2 located in 2 separate regions on one side of the diaphragm; lymph nodes and/or lymph organ
Ann Arbor: Stage 3 CA has spread to both sides of diaphragm; includes one lymph organ or area near the lymph nodes or the spleen
Ann Arbor: Stage 4 Diffuse spread to one or more extralymphatic organ or area near the lymph nodes or the spleen; liver, bone marrow, or lung involvement possible
what percent of pts are treated with surgery for CA >60%
most widely used antineoplastic drug cyclophosphamide (kill or slow down replication of tumor cells)
drug that blocks DNA synthesis (antimetabolite) methotrexate
why no exercise on chemo days high risk for cardiac arrhythmia
objective of radiation cure or control the CA via destruction of DNA
acute side effects __ to __ months 1-6
subacute side effects __ to __ months 6-12
chronic side effects __ to __ 1-5 years
Bio (Immuno) therapy objective direct or indirectly kill tumor cells through bolstering the immune system
anti-angiogenic therapy (thalidomide, angiostatin) decrease rapid blood supply development that can occur around a tumor. decreasing nutrients to tumor
leuprolide used for Prostate CA; inhibit testosterone release
tamoxifen for breast CA (inhibits estrogen release)
How long must the disease be gone before can be labeled "cured" > 5 years
complete remission all signs of disease have disappeared after tx
partial remission primary tumor reduced to 1/2 of its original size after tx
improvement primary tumor has been reduced but remains > 1/2 of its original size
prognostic index measure of risk for relapse
Created by: cdphipps21



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