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Med Surg- Ped Onco

pediatric oncology

Pediatric cancer comprises what percent of CA cases in US 2%
overall 5 year survival rate for pediatric oncology is? 80%
malignant disorder of the blood and blood-forming organs including bone marrow, lymph nodes, and spleen leukemia
lymphomas malignancy that begins in cells of the immune system
solid tumors cancers of the bone, tissues, or other organs of the body
most common form of pediatric cancer leukemia
nephroblastoma wilms tumor
common type of cancer originating in brain tissue of children astrocytoma
malignant disease that often originates in the peripheral lymph nodes hodgkins
tumor that originates in kidney wilms tumor
tumor arising most frequently in bone shaft ewings sarcoma
tumor of the eye retinoblastoma
An oncologist states that your patient's prognostic index is 40%. This means that the patient has a 40% risk for relapse.
Why should pts not participate in exercise following chemo treatment? risk of cardiac arrhythmia
primary purpose of the induction phase of tx is to: attempt to eradicate all malignant cells from the body
most serious side effect caused by anthracycline meds is cardiac myocyte apoptosis resulting in diminished heart function and altered hemodynamic response to exercise
A child with Thrombocytopenia should be monitored closely because of increased tendency to bleed or bruise, as evidenced by spontaneous nose bleeds or bleeding gums
Dysplasia D. A disorganization of cells in which an adult cell varies from its normal size, shape, or organization. It is often caused by chronic irritation. It may reverse itself or may progress to cancer.
Differentiation The process by which normal cells undergo physical and structural changes as they develop to form the different tissues of the body.
Anaplasia The most advanced form of metaplasia where there is a complete loss of cellular differentiation. Characteristic of malignant cells.
Metaplasia A reversible and benign but abnormal change in which one adult cell changes from one type to another.
Hyperplasia An increase in the number of cells in tissue, resulting in increased tissue mass. This type of change can be a normal consequence of physiologic alterations.
Why are alopecia, nausea and vomiting, and digestive tract bleeding common side effects of chemotherapy Because the body's most rapidly growing cells are very susceptible to chemotherapeutic adverse effects
serious drop in blood platelet count is known as thrombocytopenia
Thalidomide is an Anti-angiogenic therapy
_____ Inhibits estrogen release tamoxifen
Commonly prescribed for persons with prostate cancer leuprolide
One of the side effects which a child who is receiving radiation therapy may experience is hair loss resulting in temporary baldness is called allopecia
The TNM staging system stands for tumor, nodes, metastasis
intrathecal injected into CSF via catheter in lumbar or brain; commonly for methotrexate
induction phase high doses of chemo and radiation. goal to eradicate malignant cells
consolidation phase eliminate any remaining cancer cells; continue to receive chemo
maintenance phase pts receive lower doses of chemo with goal of preventing disease relapse
osteonecrosis primarily in WB bones; hips/knees most common; >10 y.o Caucasian
unexplained hip pain> 2 weeks indication for MRI, esp with gradual increase of symptoms
neurotoxicity peripheral neuropathy possible; usually wrist/finger ext to dorsiflexors
cardiotoxicity anthracyclines may cause cardiomyopathy; nearly 60% of children treated for CA use this
anthracyclines may cause cardiomyopathy;diminished heart function
BMT or PBSCT performed for children with leukemia or other hematologic diseases involving bone marrow
bone marrow is usually withdrew from where iliac crest
allogenic from donor match
autologous from yourself
syngenic from identical twin
engraftment of BM the process by which donor marrow begins to produce healthy cells; typically takes 7-10 days
acute GVHD commonly affects the skin, bowel, and liver
chronic GVHD months after transplant; affects skin and GI
GVHD transplanted marrow cells attack host organs
PT role in BMT maintain ROM, prevent atrophy, pulmonary hygiene, prevent pneumonia, maintain balance, condition
nociceptive pain aching or throbbing pain; caused by bone, joint, muscle, skin, or CT damage
neuropathic pain burning, tingling, piercing; injury to nerve
FLACC face, legs, activity, cry, consolability (birth to 5)
FACES scale 5-13
self reporting numeric scales older than 13
palliative relieving and preventing suffering
myelosuppression onset 10-20 days following drug administration
good measure for cardiopulmonary endurance in ped oncology 6 min walk test
Created by: cdphipps21



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