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IntroToPharm
| Question | Answer |
|---|---|
| Absorption | Meds going into bloodstream via GI Tract, muscle, skin, or subcutaneous tissue |
| Distribution | Transportation of meds to sites by body fluids |
| Metabolism | Changes meds into less active/inactive forms by action of enzymes. Occurs primarily in liver, can also be in kidneys, lungs, bowel, and blood. |
| Excretion | Elimination of meds from body primarily through kidneys. may also take place in liver, lungs, bowel, and exocrine glands |
| Plasma Protein binding | meds compete for protein binding site within bloodstream, mainly albumin |
| therapeutic effect | what we desire the outcome to be. |
| side effect | not main reason drug is given. unwanted outcome. |
| adverse effect | side effect has adverse/bad effect on person (vomiting, blindness, etc..) |
| Toxic effect | specific risk when too much drug is in system |
| medication interaction | how meds work/interact with other drugs, food, alcohol, etc.. |
| minimum effective concentration | smallest amount of drug that will achieve desired effect |
| toxic concentration | amount of drug that is too much, that it becomes toxic to a person |
| therapeutic range | actual amount between minimum effect and toxic effect |
| therapeutic index | increased has wide safety margin, no need for routine serum meds level monitor. decreased should have serum med level monitored closely. (peak and trough) |
| half-life | period of time needed for med to be reduced by 50% in body. may be affected by liver and kidney funtion |
| agonist | drug turning something on. causes something to happen (increase blood sugar, etc..) |
| partial agonist | blocks/stops thins from happening in body (decreased heart rate) |
| generic name | used in most drug books (ibuprofen) |
| trade name | brand name (Motrin, Advil, etc..) |
| prescription drugs | must have licensed Dr write script. controlled distribution, have more effect |
| over-the-counter drugs | may be sold at grocery store, safer, less strong |
| FDA | Food & Drug Administration |
| Teratogen | substances that are harmful to unborn fetus. |
Created by:
klevans21
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