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opiods
| Question | Answer |
|---|---|
| reverse opiods | naloxone |
| act like morphine | demerol/fentynyl and methadone/darvon |
| dilaudid | reserved for severe not relieved by ms |
| agonist-antagonist | prefered over agonist opiod r/t less abuse (ultram) |
| CNS toxic | talwin |
| tolerance | more drug needed for same effect |
| dependence | psysiological development of w/d in absence (must taper if LT use) |
| addiction | psychological dependence |
| somatic pain | well localized |
| visceral pain | poorly localized, can be referred |
| neurapathic pain | injury to CNS |
| opiod agonist | inhibit painful stimuli |
| morphine and demerol | cause histamine release > sweating/itching |
| dosing | begin RTC, also give APAP 4000 mg day if no contraind. |
| NSAIDS&APAP | dont use together, wont improve pain |
| alter pain perception | adjuvant drugs: ex gabapentin, phenytoin, clonezapam |
| new drug | use equiv. table |
| rescue dose | 5-15% of 24 hr dosing |
| opiod dosing | 24 hr and reduce by 25-50% based on age, intensity, renal/liver, etc |
| opiod dosing in elderly | reduce by 75% |
| opiods and gero | start bowel regimen |
| opiods and peds | morphine, codeine, and demerol only |
| opiods and preg | cat C also causes neonatal w/d symptoms |
| D/C of opiods | taper if LT |
| dosing of opiods | take prior to onset of severe pain |
| opiods contrain. in | IICP/head injury, liver/renal impaired/acute abdomen |
| opiod adv effects | syncope, N/V, sedation, lethargy |
| dilaudid | max analgesia effects while min. SE of morphine |
Created by:
keoughrn
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