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diuretic/E&M

AnswerHint
CAI diuretics relatively weak, contrain. in renal, sulfa allergy
Loops lasix and bumex have sulfa
loops act fast, most potent, cause K depletion, correct hyperCa
loops if fails, does no good to try another
lasix highly protein bound
loops bumex and demadex better absorbed
thiazides ineffective w/RI
thiazides good for HTN
thiazids Metalazone is strongest
thiazides can lead to gout, hypoK
thiazides good with loops
thiazides may contribute to osteoporosis
thiazides (HCTZ) glucose intolerance, decreased uric acid, and calcium excretion
thiazides worsens Lupus
Thiazide (Diuril) GFR doesnt matter
K sparing usually give w/Thiazide or loop
K spring (Na channel blockers) leads to ^K, <Na
Triamterene (Na ch bl/K sparing) can leaD TO FOLATE DEFICIENCY, GLUCOSE INTOL, AVOID ace
Amiloride (na ch bl/K sparing) effects Dig elim., lowers effect of NSAIDS, onset faster and no gynecomastia
Spironolactone (Aldosterone/K sparing) great w/high levels of aldosterone, blunts, effect of Dig, may cause gynomastia, NSAIDS lower effect
Spironolactone takes 2 days
K supp treat < 3.5, liquids >less GI irritation
K supp ck elect. 2 weeks after diuretics statred, may see wax matrix in stool, XR liquid has ducosate in it
loops increase renal vasodialation
Thiazides takes 2-4 weeks to work
hyperuricemia loops,thiazidea
geriatrics watch for ortho hypo
Created by: keoughrn
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