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AntifungalsPTCE
| Question | Answer | |
|---|---|---|
| Antifungals | MOA: prevent synth of ergosterol & inhibit fungal cytochrome P450 AR: liver toxicities (need liver tests), GI distress, photosensitivity, rashes, nausea SPECIAL: topical/systemic agents, pulse dosing rec (nail) | |
| amphotericin B | Amphotec, Fungizone, Amphocin | Antifungal Agent IV, topical |
| butenafine | Mentax | Antifungal Agent topical cream |
| ciclopirox | Loprox | Antifungal Agent topical |
| clotrimazole | Lotrimin | Antifungal Agent Oral troche, topical, vaginal |
| clotrimazole-betamethasone | Lotrisone | Antifungal Agent cream |
| fluconazole | Diflucan | Antifungal Agent IV, tab, susp (refridg 14 days) |
| griseofulvin | Grisactin, Fulvicin, Gris-PEG | Antifungal Agent take with fatty meals Cap, tab, susp |
| itraconazole | Sporanox | Antifungal Agent Cap, susp (consume cola before taking) |
| ketoconazole | Nizoral | Antifungal Agent tab, topical cream, shampoo |
| miconazole | Monistat | Antifungal Agent Topical, Vaginal |
| nystatin | Nilstat | Antifungal Agent tab, susp, topical, vaginal |
| oxiconazole | Oxistat | Antifungal Agent cream, lotion |
| sertaconazole | Ertaczo | Antifungal Agent cream |
| sulconazole | Exelderm | Antifungal Agent Cream |
| terbinafine | Lamisil | Antifungal Agent tab, topical cream, solution |
| terconazole | Terazol | Antifungal Agent vaginal cream, suppository |
| voriconazole | Vfend | Antifungal Agent IV, liquid, tab |
| Fungus | single cell organism without chlorophyll, cell wall present reproduction by spores, occurs during compromised immune system |