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AntibioticsPTCE
Question | Answer | |
---|---|---|
sulfamethoxazole-trimethroprim | Bactrim, Septra | sulfonamide suspension, tab, IV (room temp storage) |
sulfadiazine | Silvadene | sulfonamide cream |
sulfasalazine | Azulfidine | sulfonamide tab, enteric tab, supension |
sulfisoxazole | Gantrisin | sulfonamide tab, susp, ophthalmic ointment |
Penicillins | MOA: prevent bacterial cell wall CI: Abscesses, meningitis, otitis media, pneumonia, resp infections, prophylaxis AR: diarrhea, hives, rash, wheezing, anaphylaxis | SC: take on empty stomach with water, avoid taking with colas/ juice |
amoxicillin | Amoxil, Polymox | penicillin cap, susp (can store at room temp, but 14 days in fridge) |
ampicillin | Omnipen | penicillin cap, susp (7 days not refrigerated, 14 days refrigerated) |
cloxacillin | none | penicillin cap, powder for susp, powder for injection |
dicloxacillin | Dynapen | penicillin susp, tab, chewable tab |
piperacillin | none | penicillin powder for injection |
piperacillin + tazobactam | Zosyn | penicillin powder for injection, solution for injection |
penicillin | Veetids | penicillin tab, susp |
ticarcillin-clavulanate | Timentin | penicillin IV |
Cephalosporins | MOA: prevent bacterial cell wall formation CI: dental work, heart/pacemaker procedures, orthopedic surgery, pneumonia, URIs, sinus infection AR: same as penicillin, diarrhea, hives, rash, wheezing, anaphylaxis | SC: may have cross-sensitivity to penicillin |
cefaclor | Ceclor | cephalosporin cap, susp, ER tab susp: refrigerate, 14 days |
cefdinir | Omnicef | cephalosporin cap, liquid |
cefixime | Suprax | cephalosporin susp, tab |
cefepime | Maxipime | cephalosporin IV |
cefpodoxime | Vantin | cephalosporin susp |
cefadroxil | Duricef | cephalosporin cap, susp (refr- 14 days), tab |
ceftibuten | Cedax | cephalosporin susp, cap |
cefuroxime | Ceftin, Zinacef | cephalosporin IM, IV, susp (roomtemp or fridge, 10 days), tab |
cephalexin | Keflex, Keftab | cephalosporin cap, susp (fridge, 14 days), tab |
cephradine | Velosef | cephalosporin capsule |
cefprozil | Cefzil | cephalosporin liquid, cap |
Carbapenems, Carbacephems, Monobactams | CI: gram + and gram - bacteria AR: Same as penicillins/cephalosporins, increased possibility of seizures- diarrhea, hives, rash, wheezing, anaphylaxis | |
ertapenem | Invanz | carbapenem IV |
imipenem-cilastatin | Primaxin | carbapenems IV |
loracarbef | Lorabid | carbacephem cap, liquid (room temp 14 days) |
aztreonam | Azactam | monobactam IV |
Tetracyclines | MOA: inhib protein synth in bacteria by binding to ribosomes CI: acne, chronic bronchitis, lyme disease, walking pneumonia, prophylaxis for traveler's diarrhea AR: GI (n&v), photosensitivity (rashes/sunburns) | SPECIAL: may bind to antacids/dairy products, take several hours apart from products bc of possibility of chelation/ decreased efficacy of antibiotic, not for pregnant women (dental birth defects), not for children under 9, expired can cause toxicity/deat |
doxycycline hyclate | Vibramycin | tetracycline cap, iv, susp (protect from light, room temp 14 days), tab |
doxycycline monohydrate | Monodox | tetracycline tab |
minocycline | Minocin | tetracycline Cap, IV, susp, tab |
tetracycline | Achromycin, Sumycin | tetracycline cap, susp, topical |
Macrolides | MOA: inhib protein synthesis by combo w ribosomes CI: Pulmonary infections, chlamydia, Haemophilus influenza AR: GI distress | SPECIAL: take with food |
azithromycin | Zithromax | Macrolide cap, susp (refrig 10 days) |
clarithromycin | Biaxin | Macrolide granule for oral susp (not refrig 14 days), film coated tablet |
dirithromycin | Dynabac | Macrolide Enteric coated tab |
erythromycin base | Eryc, E-Mycin, Ery-Tab | Macrolide cap, tab, EC tab, film-coated tab |
erythromycin estolate | Ilosone | Macrolide cap, susp, tab |
erythromycin ethylsuccinate | E.E.S. | Macrolide susp, tab, chew tab |
erythromycin stearate | Erythrocin | Macrolide film-coated tab, IM (use within 8 hrs of recons), iV |
erythromycin-sulfisoxazole | Pediazole | Macrolide oral susp |
erythromycin lactobionate | Erythrocin | Macrolide IV |
Ketolides | MOA: block protein synth by binding to ribosomal subunits; may inhibit formation of newly forming ribosomes CI: bacterial infections of lungs/sinuses AR: blurred vision, GI distress (like macrolide) | |
telithromycin | Ketek | ketolide tab |
Quinolones | MOA: Antagonize enzyme responsible for collecting/replicating DNA, leading to DNA breakage/death CI: bone/joint infections, dental work, infectious diarrhea, URIs, UTIs AR: N&V, joint swelling, dizziness | Special: Antacids interfere w/ absorption, may cause toxicity, photo toxicity, tendon damage under 18 yrs old, no pregnant women |
cinoxacin | Cinobac | Quinolones cap |
ciprofloxacin | Cipro | Quinolones tab, susp, ophthalmic, IM (protect from light), IV |
gatifloxacin | Tequin | Quinolones tab, IM, IV |
levofloxacin | Levaquin | Quinolones IV, Tab |
lomefloxacin | Maxaquin | Quinolones Tab |
moxifloxacin | Avelox, Vigamox | Quinolones tab |
norfloxacin | Noroxin | Quinolones tab |
ofloxacin | Floxin, Ocuflox | Quinolones tab, IV (protect from light), ophthalmic |
Streptogramins | MOA: inhib protein synth in bacterial ribosomes CI: Gram + infections, enteroccocus faecium, vancomycin/methicillin-resistant infections AR: N&V, joint swelling, dizziness, site of infusion reaction | Special: IV lines must be flushed with D5W |
quinupristin-dalfopristin | Synercid | Streptogramin IV- not come into contact with saline or other meds, store in fridge |
Aminoglycosides | MOA: inhib bact synth by binding to ribosomal subunits CI: Life threatening infections, sepsis, immunocompromised patients AR: nephrotoxicity, ototoxicity, tinnitus, permanent deafness | Special: adjust dose for each patient after first dose, once per day dosage tends to reduce toxicity |
amikacin | Amikin | aminoglycoside injection |
gentamicin | Garamycin | aminoglycoside cream, IM, IV, ophthalmic |
neomycin | Mycifradin | aminoglycoside Tab, solution, IM, cream, ointment |
streptomycin | Strptomycin | aminoglycoside IM, iV |
tobramycin | Nebcin | aminoglycoside IV, ophthalmic |
Cyclic Lipopeptides | MOA: Bind to bact. membranes, cell memb depolarized and inhibit RNA/DNA synth CI: complicated skin infections, aerobic gram + bacterial infections AR: Hypotension, headache, insomnia, allergic site reactions | SPECIAL: dont take with 3- hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors |
daptomycin | Cubucin | Cyclic Lipopeptide IV |
clindamycin | Cleocin | Misc. Antibiotic MOA: inhib prot synth CI: acne, dental prophylaxis for pen allergic patients, anaerobic pneumonia, bone infections, genital infections AR: bloody diarrhea |
metronidazole | Flagyl | Misc. Antibiotic MOA: destroys bacteria's DNA nucleus CI: Trichomonas infections of vagina/cervix/male urethra, amebic dysentry, intestinal infections AR: metallic taste, diarrhea, rash, "Antabuse-like reaction" with alcohol SPECIAL: take w food, av |
pentamidine | NebuPent, Pentam | misc. Antibiotic MOA: unknown CI: treat pneumocystis carinii infection AR: Hypotension, wheezing, coughing SPECIAL: if inhaled, must be diluted w/ sterile water. Nebulize at 6mL/min |
linezolid | Zyvox | Misc. Antibiotics MOA: inhib bact protein synth CI: MRSA and Vanc. resistant E. faecium, gram + infections SPECIAL: IV protect from light, cannot be admin w/ other meds |
vancomycin | Vancocin | MOA: inhib bact wall formation CI: dialysis patients, endocarditis, staphylococcus infections AR: ototoxicity, nephrotoxicity, neutropenia SPECIAL:CDC guidelines for use (overused), patients need to be kept hydrated |
Sulfonamides:Bacteriostatic | MOA: para-amino-benzoic acid/folic acid formation interference CI: UTIs, otitis media, ulcerative colitis, lower resp infection AR: photosensitivity- rash/sunburn, N&V, jaundice, blood complications, kidney damage | SC: avoid direct sunlight, lots of water (crystallized urine) |