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AntibioticsPTCE

QuestionAnswer
sulfamethoxazole-trimethroprim Bactrim, Septra sulfonamide suspension, tab, IV (room temp storage)
sulfadiazine Silvadene sulfonamide cream
sulfasalazine Azulfidine sulfonamide tab, enteric tab, supension
sulfisoxazole Gantrisin sulfonamide tab, susp, ophthalmic ointment
Penicillins MOA: prevent bacterial cell wall CI: Abscesses, meningitis, otitis media, pneumonia, resp infections, prophylaxis AR: diarrhea, hives, rash, wheezing, anaphylaxis SC: take on empty stomach with water, avoid taking with colas/ juice
amoxicillin Amoxil, Polymox penicillin cap, susp (can store at room temp, but 14 days in fridge)
ampicillin Omnipen penicillin cap, susp (7 days not refrigerated, 14 days refrigerated)
cloxacillin none penicillin cap, powder for susp, powder for injection
dicloxacillin Dynapen penicillin susp, tab, chewable tab
piperacillin none penicillin powder for injection
piperacillin + tazobactam Zosyn penicillin powder for injection, solution for injection
penicillin Veetids penicillin tab, susp
ticarcillin-clavulanate Timentin penicillin IV
Cephalosporins MOA: prevent bacterial cell wall formation CI: dental work, heart/pacemaker procedures, orthopedic surgery, pneumonia, URIs, sinus infection AR: same as penicillin, diarrhea, hives, rash, wheezing, anaphylaxis SC: may have cross-sensitivity to penicillin
cefaclor Ceclor cephalosporin cap, susp, ER tab susp: refrigerate, 14 days
cefdinir Omnicef cephalosporin cap, liquid
cefixime Suprax cephalosporin susp, tab
cefepime Maxipime cephalosporin IV
cefpodoxime Vantin cephalosporin susp
cefadroxil Duricef cephalosporin cap, susp (refr- 14 days), tab
ceftibuten Cedax cephalosporin susp, cap
cefuroxime Ceftin, Zinacef cephalosporin IM, IV, susp (roomtemp or fridge, 10 days), tab
cephalexin Keflex, Keftab cephalosporin cap, susp (fridge, 14 days), tab
cephradine Velosef cephalosporin capsule
cefprozil Cefzil cephalosporin liquid, cap
Carbapenems, Carbacephems, Monobactams CI: gram + and gram - bacteria AR: Same as penicillins/cephalosporins, increased possibility of seizures- diarrhea, hives, rash, wheezing, anaphylaxis
ertapenem Invanz carbapenem IV
imipenem-cilastatin Primaxin carbapenems IV
loracarbef Lorabid carbacephem cap, liquid (room temp 14 days)
aztreonam Azactam monobactam IV
Tetracyclines MOA: inhib protein synth in bacteria by binding to ribosomes CI: acne, chronic bronchitis, lyme disease, walking pneumonia, prophylaxis for traveler's diarrhea AR: GI (n&v), photosensitivity (rashes/sunburns) SPECIAL: may bind to antacids/dairy products, take several hours apart from products bc of possibility of chelation/ decreased efficacy of antibiotic, not for pregnant women (dental birth defects), not for children under 9, expired can cause toxicity/deat
doxycycline hyclate Vibramycin tetracycline cap, iv, susp (protect from light, room temp 14 days), tab
doxycycline monohydrate Monodox tetracycline tab
minocycline Minocin tetracycline Cap, IV, susp, tab
tetracycline Achromycin, Sumycin tetracycline cap, susp, topical
Macrolides MOA: inhib protein synthesis by combo w ribosomes CI: Pulmonary infections, chlamydia, Haemophilus influenza AR: GI distress SPECIAL: take with food
azithromycin Zithromax Macrolide cap, susp (refrig 10 days)
clarithromycin Biaxin Macrolide granule for oral susp (not refrig 14 days), film coated tablet
dirithromycin Dynabac Macrolide Enteric coated tab
erythromycin base Eryc, E-Mycin, Ery-Tab Macrolide cap, tab, EC tab, film-coated tab
erythromycin estolate Ilosone Macrolide cap, susp, tab
erythromycin ethylsuccinate E.E.S. Macrolide susp, tab, chew tab
erythromycin stearate Erythrocin Macrolide film-coated tab, IM (use within 8 hrs of recons), iV
erythromycin-sulfisoxazole Pediazole Macrolide oral susp
erythromycin lactobionate Erythrocin Macrolide IV
Ketolides MOA: block protein synth by binding to ribosomal subunits; may inhibit formation of newly forming ribosomes CI: bacterial infections of lungs/sinuses AR: blurred vision, GI distress (like macrolide)
telithromycin Ketek ketolide tab
Quinolones MOA: Antagonize enzyme responsible for collecting/replicating DNA, leading to DNA breakage/death CI: bone/joint infections, dental work, infectious diarrhea, URIs, UTIs AR: N&V, joint swelling, dizziness Special: Antacids interfere w/ absorption, may cause toxicity, photo toxicity, tendon damage under 18 yrs old, no pregnant women
cinoxacin Cinobac Quinolones cap
ciprofloxacin Cipro Quinolones tab, susp, ophthalmic, IM (protect from light), IV
gatifloxacin Tequin Quinolones tab, IM, IV
levofloxacin Levaquin Quinolones IV, Tab
lomefloxacin Maxaquin Quinolones Tab
moxifloxacin Avelox, Vigamox Quinolones tab
norfloxacin Noroxin Quinolones tab
ofloxacin Floxin, Ocuflox Quinolones tab, IV (protect from light), ophthalmic
Streptogramins MOA: inhib protein synth in bacterial ribosomes CI: Gram + infections, enteroccocus faecium, vancomycin/methicillin-resistant infections AR: N&V, joint swelling, dizziness, site of infusion reaction Special: IV lines must be flushed with D5W
quinupristin-dalfopristin Synercid Streptogramin IV- not come into contact with saline or other meds, store in fridge
Aminoglycosides MOA: inhib bact synth by binding to ribosomal subunits CI: Life threatening infections, sepsis, immunocompromised patients AR: nephrotoxicity, ototoxicity, tinnitus, permanent deafness Special: adjust dose for each patient after first dose, once per day dosage tends to reduce toxicity
amikacin Amikin aminoglycoside injection
gentamicin Garamycin aminoglycoside cream, IM, IV, ophthalmic
neomycin Mycifradin aminoglycoside Tab, solution, IM, cream, ointment
streptomycin Strptomycin aminoglycoside IM, iV
tobramycin Nebcin aminoglycoside IV, ophthalmic
Cyclic Lipopeptides MOA: Bind to bact. membranes, cell memb depolarized and inhibit RNA/DNA synth CI: complicated skin infections, aerobic gram + bacterial infections AR: Hypotension, headache, insomnia, allergic site reactions SPECIAL: dont take with 3- hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
daptomycin Cubucin Cyclic Lipopeptide IV
clindamycin Cleocin Misc. Antibiotic MOA: inhib prot synth CI: acne, dental prophylaxis for pen allergic patients, anaerobic pneumonia, bone infections, genital infections AR: bloody diarrhea
metronidazole Flagyl Misc. Antibiotic MOA: destroys bacteria's DNA nucleus CI: Trichomonas infections of vagina/cervix/male urethra, amebic dysentry, intestinal infections AR: metallic taste, diarrhea, rash, "Antabuse-like reaction" with alcohol SPECIAL: take w food, av
pentamidine NebuPent, Pentam misc. Antibiotic MOA: unknown CI: treat pneumocystis carinii infection AR: Hypotension, wheezing, coughing SPECIAL: if inhaled, must be diluted w/ sterile water. Nebulize at 6mL/min
linezolid Zyvox Misc. Antibiotics MOA: inhib bact protein synth CI: MRSA and Vanc. resistant E. faecium, gram + infections SPECIAL: IV protect from light, cannot be admin w/ other meds
vancomycin Vancocin MOA: inhib bact wall formation CI: dialysis patients, endocarditis, staphylococcus infections AR: ototoxicity, nephrotoxicity, neutropenia SPECIAL:CDC guidelines for use (overused), patients need to be kept hydrated
Sulfonamides:Bacteriostatic MOA: para-amino-benzoic acid/folic acid formation interference CI: UTIs, otitis media, ulcerative colitis, lower resp infection AR: photosensitivity- rash/sunburn, N&V, jaundice, blood complications, kidney damage SC: avoid direct sunlight, lots of water (crystallized urine)
Created by: 669630528
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