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ACHE Inhibitors

Cholinesterase Inhibitors

QuestionAnswer
What are the reversible cholinesterase inhibitors used to treat Myasthinia Gravis? Neostigmine, Ambenonium, Edrophonium, Pyridostigmine
What are the reversible cholinesterase inhibitors used to treat Alzheimer's? Donepezil, Galentamine, Rivastigmine, Tracine
What's an irrevesible cholinesterase inhibitor? Echothiosphate
Used to treat myasthenia gravis: Ambenonium, Edrophonium, neostigmine
Why are cholinesterase inhibitors so dangerous? They are highly lipid soluble and can pass through membrane easily. They bind to the cholinesterase for a long time.
Ambenomium myasthenia gravis
Edrophonium myasthenia gravis
Neostigmine myasthenia gravis
Pyridostigmine myasthenia gravis
Physiostigmine Similar to neostgmine
Therapeutic Use of irrevesible cholinesterase inhibitor: Glaucoma treatment
Echothiophate Use to treat glaucoma
Toxic effects of cholinesterase inhibitors Overstimulation of muscarinic receptors
What drug can be used to treat an overdose? Pralidoxime.
Tracine Used to treat alzheimers
Donepezil Used to stimulate ach receptors in the CNS
Created by: ekm