Drugs for Biochem class
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| Inhibits both COX-1 and COX-2, but does not reduce inflammation | Acetaminophen
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| Inhibits COX-1 slightly more than COX-2 | Acetaminophen
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| Inhibits transcription and replication by physically obstructing polymerase | Actinomycin D
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| A class of polypeptide antibiotic, derived from soil bacteria of the genus Streptomyces | Actinomycin D
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| Binds DNA at the transcription initiation complex and interferes with DNA replication | Actinomycin D
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| Suicide inhibitor of xanthine oxidase | Allopurinol
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| Prevents hyperuricemia | Allopurinol
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| Inhibits xanthine oxidase | Allopurinol
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| Inhibits eukaryotic mRNA synthesis | alpha-amanitin
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| Product of toxic mushroom, Amanita phalloides | alpha-amanitin
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| Binds to RNA pol II and inhibits elongation | alpha-amanitin
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| Used as a research tool to investigate mRNA synthesis | alpha-amanitin
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| Inhibits COX-1 | Aspirin
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| Inhibits peptide bond formation by peptidyltransferase (23S rRNA) between the P site peptide and the A site amino acid | Chloramphenicol
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| Inhibits translation by inhibiting peptidyltransferase (50S) in prokaryotes | Chloramphenicol
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| Inhibits peptidyltransferase | Chloramphenicol (prokaryotes) and Cyclohexamide (eukaryotes)
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| Inhibits peptidyltranferase (50S) in prokayrotes | Chloramphenicol
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| Inhibits DNA gyrase | Ciprofloxacin
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| Inhibits peptidyltransferase | Cycloheximide
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| Inhibits eukaryotic peptidyl transferase | Cycloheximide
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| Inihibits translation by inhibiting peptidyltransferase (eukaryotic 60S) in eukaryotes | Cycloheximide
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| Inhibits peptidyltransferase (60S) in eukaryotes. | Cycloheximide
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| Interferes with the translocation step in protein synthesis | Cycloheximide
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| Interferes with movement of two tRNA molecules and mRNA in relation to the ribosome | Cycloheximide
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| Blocks translational elongation by inhibiting peptidyltransferase (60S) in eukaryotes | Cycloheximide
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| Prevents translocation of aa-tRNA to the A site of ribosomes | Erythromycin
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| Inhibits translation by binding to the entrance of the exit tunnel on the 50S subunit blocking elongation | Erythromycin
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| Inhibits translation by preventing translocation (50S) in prokaryotes | Erythromycin
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| Prevents translocation (50S) in prokaryotes | Erythromycin
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| Inhibitor of dihydrofolate reductase | Methotrexate
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| Inhibits dihydrofolate reductase | Methotrexate
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| Competitive inhibitor of human dihydrofolate reductase | Methotrexate
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| Increases extracellular adenosine | Methotrexate
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| Inhibits peptide bond formation by binding to the A-site and inducing peptide bond formation causing premature termination of translation | Puromycin
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| Causes chain termination in both prokaryotes and eukaryotes | Puromycin
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| Inhibts translation by causing premature termination with a tyrosinyl-tRNA analog in both eukaryotes and prokaryotes | Puromycin
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| Premature termination (tyrosinyl-tRNA analog) in both prokaryotes and eukaryotes | Puromycin
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| Inhibits bacterial RNA polymerase and is therefore used to treat tuberculosis | Rifampin (rifampicin)
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| Inhibits bacterial RNA polymerase | Rifampin (rifampicin)
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| An inhibitor of prokaryotic RNA polymerase | Rifampin (rifampicin)
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| Class of drugs that inhibit HMG-CoA due to a structural similarity to mevalonate | Statins
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| HMG-CoA reductase inhibitor | Statins
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| A class of hypolipidemic drugs used to lower cholesterol levels | Statins
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| Inhibits HMG-CoA reductase | Statins
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| Inhibits the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis | Statins
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| Prevents initiation of translation and causes misreading of codons | Streptomycin
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| Causes misreading of codons and inaccurate initiation | Streptomycin
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| Inihibits initiation in bacteria | Streptomycin
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| Inhibits translation by preventing initiation and causing misreading (30S) | Streptomycin
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| Prevents initiation and causes misreading (30S) in prokaryotes. | Streptomycin
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| Inhibits elongation in bacteria by inhibiting GTP hydrolysis to relase EF-Tu from the ribosome | Tetracycline
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| Inhibits translation by prevent aminoacyl-tRNA binding (30S) in prokaryotes | Tetracycline
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| Inhibits binding of aminoacyl-tRNA to A site of ribosomes | Tetracycline
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| Prevent aa-tRNA binding (30S) in prokaryotes | Tetracycline
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