| Question |
Answer |
| Glucokinase synthsis is induced by ___________ |
insulin |
| PFK2 is activated to make Fructose-2,6 bisphosphate by _____________ |
insulin |
| Fructose-2,6 bisphosfate activates |
PFK |
| Pyruvate kinase is active when dephosphoylated at |
high insulin/glucagon ratios |
| Pyruvate dehdyrogenase is induced by |
insulin in addition to intracellular activation |
| Excess NADH in the fed state will inhibit _______ in the Kreb cycle |
isocitrate dehydrogenase |
| Inhibition of isocitrate dehydrogenase causes a build up of ____________. |
Citrate |
| FA synthesis is induced by _____________ |
insulin |
| Acetyl CoA Carboxylase Regulation (4) |
1. CoA carboxylase synthesis is induced by insulin.
2. active when dephosphorylated/inactive when phosphorylated
3. allosterically inhibited by palmitoyl CoA
4. Allosterically activated by citrate |
| What inhibits carnitine trasport of fatty acyl groups into the mitochondrion |
Malonyl CoA |
| Lipoprotein lipase synthesis and secretion is induced by ____________. |
Insulin |
| Lipoprotein lipase occurs where? |
capillary endothelial cells and in adipose and skeletal muscle tissues |
| Whihc has lower Km --> adipose lipoprotein lipase or muscle lipoprotein lipase |
Skeletal muscle lipoprotein lipase |
| What happens to FA in muscle |
breakdown to CO2 and H2O |
| What happens to FA in adipose |
TG storage |
| Insulin's effect on adipocytes |
increases glucose availability for glycerol 3 phosphate synthesis |
Beef Production
