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Sherer Ch3

QuestionAnswer
First reports of somatic damage Europe 1896
First American fatality from radiation Clarence Madison Dally October 1904
Physician reported cancer deaths from x-ray exposure first reported in? 1910
radiation exposure received by radiation workers in the course of exercising their professional responsibilities occupational exposure
reddening of the skin radiodermatitis
results from bone marrow failure aplastic anemia
abnormal overproduction of white blood cells leukemia
received quantity of rad. that causes diffuse redness over an area of skin after radiation. unit for measuring radiation exposure from 1900-1930 skin erythema dose
"Roentgen" accepted unit of exposure, ICRU charged with defining unit. Established Intern'tl X-Ray & Radium Protection Commission Second International Congress of Radiology in Stockholm Sweden, 1928
appear within minutes, hours, days, or weeks of the time of radiation exposure. short term somatic effects (acute or early effects)
nausea, fatigue, loss of hair, fever, diffuse redness of skin, blood disorders, shedding of the outer layer of skin short term somatic effects (acute or early effects) of radiation exposure
radiation dose to which occupationally exposed persons could be continuously subjected without any apparent harmful acute effects tolerance dose
dose of radiation below which an individual has a negligible chance of sustaining specific biologic damage threshold dose
recommended tolerance dose daily limit by International Protection Commission & US Advisory committee 1931/1934 .2 roentgen
daily dose limit in 1936 .1 roentgen
Cancer, Embryologic effects (birth defects), formation of cataracts, genetic (heritable) effects Long term (late) somatic effects of radiation exposure
appear months or years after radiation exposure Long term (late) somatic effects of radiation exposure
Makes possible the interchange of units among all branches of science throughout the world. International System of units (SI)
Maximum Permissible Dose (MPD) replaced tolerance dose for rad prot. 1950's
indicated largest dose of rad an occupationally exposed person was permitted that was not anticipated to result in major adverse bio fx MPD Maximum permissible dose (expressed in rem)
recommendations for dose limits based on what? probability of harm associated with typical film badge reading should not exceed amt of harm in industries generally considered safe.
Rad units developed that contained factors that accounted for varied bio fx of different types of radiation 1970's
when did recognition come that health consequences based upon which organs had been irradiated 1970's
safe occupation are considered to have what risk of death 10^-4/yr
IRCP revised tissue weighting factors based on data from recent studies of atomic bomb survivors 1991
Effective Dose (EfD) adopted 1991
takes into account type or radiation & variable sensitivity of tissues exposed to radiation Effective Dose (EfD)
Measure of overall risk arising from irradiation of biologic tissue & organs Effective Dose (EfD)
measurement for exposure to x-radiation & gamma radiation Roentgen (R)
photon exposure that under standard conditions of pressure and temp produces a total + or - ion charge of 2.58x(10^-4) C/kg 1 roentgen
unit for dose that is equivalent to any type of ionizing radiation that produces the same effect as 1 rad of x-radiation Rem
what does rem stand for? radiation equivalent man
what are fluoroscopic entrance rates measured in? roentgens per minute (R/min)
relates the ionization produced in a small cavity within an irradiated medium to the energy absorbed in that medium Bragg-Gray theory 1936
links determination of absorbed dose in a medium to a relatively simple measurement of ionization charge Bragg-Gray theory 1936
swedish physicist best known for method of determining exposure rates at various poins near linear radium sources Rolf Maximilian Sievert
amount of ionizing radiation that may strike an object such as the human body when in the vicinity of a rad source Exposure (X)
deposition of energy per unit mass by ionizing radiation in the patient's body tissue absorbed dose (D)
attempt to take into account the variation biologic harm that is produced by different types of rad. Equivalent Dose (EqD)
attempts to summarize the overall potential for biologic damage to a human from exposure to ionizing radiation Effective Dose (EfD)
radiation ionization in air exposure
total electrical charge of one sign per unit mass that x-ray & gamma photons with energies up to 3MeV generate in dry air at atmosphere exposure
basic unit of electric charge Coulomb
quantity of electrical charge flowing past a point in a circuit 1 second when an 1 amp used Coulomb
SI unit of exposure C/kg
Roentgens to Coulombs/kg R x 2.58 x (10^-4)
Coulombs/kg to Roentgens C/kg รท 2.58 x (10^-4) or C/kg x 3.88x(10^3)
responsible for any biologic damage resulting from the tissues being exposed to radiation absorbed dose (D)
factors controlling absorption of radiation Z# of tissue, mass density of tissue, energy of incident photon
factors causing increased absorption higher Z#, higher mass density, lower photon energy
factors causing increased transmission lower Z#, lower mass density, higher photon energy
composite or weighted average of atomic numbers of the chemical elements that comprise a tissue Effective Atomic Number (Zeff)
Zeff of bone 13.8
Zeff of soft tissue 7.4
in diagnostic range (23-150kVp) which absorbs more energy, bone or soft tissue? bone
what happens to absorption in therapeutic range (100keV +) difference in absorption gradually lessens, absorption decreases, scatter increases as beam energy increases.
which atomic numbers more likely to produce compton scatter? none, Z# has no influence
relationship between mass density and effect on absorption direct linear proportionality, double mass density, double absorption
energy of absorption or 1 joule (J) per kg of matter in the irradiated object Gray (Gy)
SI unit of absorbed dose Gray (Gy)
unit of energy, work done or energy expended when a force of 1 newton acts on a single object alone a distance of 1 meter Joule (J)
Traditional unit of measure for absorbed dose Rad (radiation absorbed dose)
used to indicate amount of radiant energy transferred to an irradiated object by any type of ionizing radiation. Rad (radiation absorbed dose)
adjustment multiplier used in the calculation of dose equivalence to specify the ability of a dose to cause biologic damage Quality Factor (Q)
amount of energy xfrd on average by incident radiation to an object per unit length of track through the object and is expressed in keV/micrometer LET - Linear Energy Transfer
radiation with high LET transfers can do more biologic damage, why? it transfers a large amount of energy into a small area
corresponds to type and energy of radiation for determining equivalent dose radiation weighting factor (Wr)
weighting factor corresponds to what other numeric value? quality factor
How do you determine EqD? EqD = D x Wr (Sv = Gy x Wr)
conceptual measure for relative risk associated with irradiation of different body tissues Tissue Weighting Factor (Wt)
Value that denotes the percentage of the summed stochastic risk stemming from irradiation of tissue to the all inclusive risk Tissue Weighting Factor (Wt)
Tissue Weighting factor for gonads 0.20
Tissue Weighting factor for active bone marrow, colon, lung, & stomach 0.12
Tissue Weighting factor for the breast, bladder, esophagus, liver, thyroid 0.05
Tissue Weighting factor for bone surface & skin 0.01
How do you determine EfD? EfD = D x Wr x Wt
describes radiation exposure of a population or group from low doses of different sources of ionizing radiation. Collective Effective Dose (ColEfD)
determined as the product of the average EfD for an individual belonging to exposed population or group and the # of persons exposed Collective Effective Dose (ColEfD)
1 Sievert is equal to? 1 J/kg (for x-ray Q=1) 100 rem 100 cSv 1000 mSv
1 Gray is equal to? 1 J/kg 100 rad 100 cGy 1000 mGy
1 rad is equal to? 1/100 J/kg 1/100 Gy 1 cGy
1 rem is equal to? 1/100 J/kg 1/100 Sv 1 cSv 10 mSv
1 roentgen is equal to? 2.58 x (10^-4) C/kg of air
the radiation quantity that can be used to compare the average amount of radiation received by the entire body from a specific radiologic examination with the amount received from natural background radiation EfD
Zeff of air 7.6
quantity that reflects dose & volume of tissue irradiated. measured in cGy-cm^2 Dose Area Product (DAP)
increases with increasing field size, even if dose remains the same DAP
Created by: jen.studer
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