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MCATBio Renal+Digest
Term | Definition |
---|---|
colon | this excretory organ reabsorbs water and eliminates solid waste (material eaten but NOT absorbed in blood) |
liver | this excretory organ eliminates hydrophobic waste (fat, cholesterol) --> material eaten AND absorbed in blood BUT too hydrophobic to dissolve in plasma |
kidney | this excretory organ eliminates hydrophilic waste, which includes material eaten, absorbed and dissolved in blood, and filtered out of plasma |
kidney | this excretory organ regulates BP ion balance, water balance, pH; secretes erythropoietin, performs small amount gluconeogenesis; responsible for activation of vitamin K |
erythropoietin | secretion of ______________ by the kidneys increases RBC formation |
adrenal | ___________ glands sit on top of the kidneys but are not apart of the renal system |
internal | __________ urinary sphincter is made up of smooth muscle; involuntary control |
external | ___________ urinary sphincter is made up of skeletal muscle; voluntary control |
ureter | the ________ connects the kidney to the bladder |
cortex | the outer layer of the kidney |
medulla | the inner layer of the kidney |
nephron | functional unit of a kidney |
renal pelvis | the connecting point between the medulla and the ureter; once urine reaches this point, no further modifications are made |
increases | osmolarity _____________ as you move from cortex to medulla because solute concentration is increasing |
in, out | water moves ____ to the medulla and ____ of the nephron in the medulla |
loops of henle | these are structures of nephrons - can be long or short |
long | (long/short) loops of henle perform water retention better and are found in animals such as camels and other desert animals |
short | (long/short) loops of henle don't enter as far into the nephron so they don't perform water retention the best and are found in freshwater animals such as manatees |
urine | nephrons make _______ |
filtration | - first step in process to produce urine - moves a substance (blood plasma) across a membrane (capillary wall) using pressure (BP) |
plasma, proteins | capillary wall membranes are fenestrated: this allows the diffusion of primarily water and things found in _______: the membrane allows the diffusion of these things EXCEPT ________ and large blood cells |
reabsorption | - second step in process to produce urine - moves a substance from the filtrate (sitting in the nephron) back into the blood - glucose, amino acids - water (based on the body's needs) |
secretion | - third step in process to produce urine - moves a substance from the blood back into the filtrate - drugs, toxins, creatine |
afferent arterioles | this group of vessels bring blood into the capsule of the nephron |
efferent arterioles | this group of vessels bring blood away from the capsule of the nephron |
glomerulus | a network of capillaries in the capsule of the nephron where filtration occurs |
dilate, constrict | you want more blood going into capsule than leaving ∴ afferent arterioles should _________ efferent arterioles should _________ |
bowman's capsule | the first part of the nephron in which filtration takes place (full name) |
proximal convoluted tubule | the first part of the tubule (PCT) closest to the capsule in which reabsorption and secretion takes place; mostly unregulated |
reabsorbed | at the proximal convoluted tubule - glucose, amino acids, H+, and H20 are _____________ (--> medulla) |
loop of henle | this structure of the nephron directly follows the proximal tubule - two parts: descending and ascending limb - two parts have opposite permeabilities to water and sodium |
descending, out | in the ___________________ limb of the loop of henle - high permeability to H2O --> H2O diffuses ______ the nephron - impermeable to Na+ |
ascending, out | in the ___________________ limb of the loop of henle - impermeable to water - high permeability to Na --> Na+ diffuses ______ the nephron |
distal convoluted tubule | the second part of the tubule (DCT) farthest from the capsule has specialized reabsorption and secretion due to high regulation by the hormone, aldosterone |
aldosterone | _____________ increases Na+ reabsorption and increases K+ secretion in the distal convoluted tubule of the nephron in the kidney |
collecting duct | this part comes directly after the nephron and regulates H2O reabsorption via aquaporin channels |
ADH | the permeability of aquaporin channels is dependent on whether ______ is present |
open | when ADH is present, aquaporins will _____ and H2O will be reabsorbed back into the blood stream |
vasa vecta | capillaries that wrap around the loop of henle |
capillaries | H2O leaving the loop of henle is taken up by ___________ called the vasa vecta |
efferent | H2O taken up by the vasa vecta transported to the _________ arteries |
decreases | as urine volume increases --> urine concentration __________ |
decreases | as urine volume increases --> blood volume ____________ |
drop | a (drop/raise) in blood pressure is more deadly |
renin | when blood pressure drops, kidneys secrete _______ |
angiotensin I | when kidney secrete renin, angiotensinogen is converted to ___________ __ |
ACE | angiotensin I is converted into angiotensin II with the help of __________ |
vasoconstriction | angiotensin II causes systemic _______________ which increases BP |
decreases | systemic vasoconstriction (caused by angiotensin II) causes the afferent arteriole to constrict, which ____________ blood flow into the nephron |
aldosterone, decreases | angiotensin II increases ____________ release from the kidneys --> increases Na+ reabsorption --> increases blood osmolarity --> _______ blood volume |
ADH, increases | low blood volume due to high blood osmolarity triggers _____ to be released to compensate ---> _________ water reabsorption --> increases blood volume --> increases BP |
juxtaglomerular apparatus | connecting point between the afferent arteriole and the distal convoluted tubule; JGA |
baroreceptors | the side of the JGA closest to the afferent arteriole has lots of ____________ which detect pressure changes |
chemoreceptors | the side of the JGA closest to the distal convoluted tubule, there are lots of ____________ which detect changes in concentration (osmolarity) |
decreases, renin, increase | when filtrate osmolarity __________, the JGA closest to the DCT stimulates the afferent arterioles to release ________ and directly dilates the afferent arterioles --> _________ filtration rate through the kidney |
ANP | when BP increases, the atria stretch, and the R. atrium release ________ |
vasodilation, inhibits | ANP causes ___________ in the muscles of the arterial walls and _____________ renin release --> decreases BP |
slow | renal regulation of blood pH is (slow/fast) |
fast | respiratory regulation of blood pH is (slow/fast) |
carbonic anhydrase | CO2 + H2O is converted into H2CO3 by ___________ ________, which is immediately converted into H+ and HCO3- |
acidic | the kidneys primarily secrete H+ and reabsorb HCO3-, which makes urine ____________ |
alimentary canal | long muscular tube that goes from mouth to anus |
bile | the liver makes _________ which is amphipathic and facilitates fat digestion |
bile | _____________ surrounds smaller fat globules and allows digestive enzymes to access the fat and further break it down |
gallbladder | stores and concentrates bile; you can live without this but will need a low fat diet |
glucose | the endocrine part of the pancreas regulates blood _______ levels via insulin and glucagon (endocrine role) |
digestive, secretes | the pancreas is the main source of many _________ enzymes and ________ HCO3- to neutralize the acidic pH of the stomach |
narrows | when the circular muscles of the alimentary canal wall contracts --> the tube __________ |
shortens | when the longitudinal muscles of the alimentary canal wall contracts --> the tube _______ |
wave of peristalsis | circular and longitudinal muscles work together by contracting to push bolus of food down the canal |
mouth | the function of the __________ is to grind food, moisten food, and begin starch + lipid digestion |
saliva | the exocrine glands of the mouth secrete _______, which is composed mainly of water, as well as lysozymes, amylases, and lingual lipases |
esophagus | the function of the ___________ is to act as a tube that carries food down to the stomach |
smooth | the esophagus starts as skeletal muscle and becomes __________ muscle |
cardiac sphincter | this structure of the esophagus prevents the reflux of stomach contents; aka. the lower esophageal sphincter |
mucus | the exocrine gland in the esophagus releases ________ |
zymogen | this refers to an inactive, digest enzyme |
stomach | the function of the __________ actually involves very little digestion and absorption and primarily acts as a tank for food, but does some acid hydrolysis |
gastric | the stomach contains _________ glands, which include cheif, parietal, and mucus cells, which are examples of exocrine glands |
chief | __________ cells make pepsinogen |
parietal | __________ cells secrete HCl to make the environment of the stomach acidic |
mucus | __________ cells secrete mucus which protects the stomach cells (lining) |
activated | pepsinogen is _________ when it comes in contact with acid in order to make pepsin |
G-cells | the endocrine glands of the stomach include __________, which secrete gastrin, activate gastrin glands, and is involved with negative feedback via acid |
small intestine | this part of the digestive system is where virtually all digestion and absorption occurs; 3 regions: duodenum --> jejunum --> ileum |
enterokinase, trypsin | ______________ is an exocrine enzyme in the small intestine that activates one of the pancreatic zymogens, trypsinogen, which when activated becomes ___________, which sends off a cascade of activating other pancreatic enzymes |
brush border | __________ ____________ enzymes create monomers for absorption and is the final step in digestion |
enterogastrone | this is an endocrine hormone in the small intestine that slows down stomach emptying and motility |
CCK | this is an endocrine hormone that stimulates bile release |
secretin | this is an endocrine hormone that stimulates the release of HCO3- |
large intestine | this part of the digestive system mainly involves reabsorption of water and storage of feces |
bacteria | ________ in the large intestine secrete vitamin K which results in blood clotting; eats up any remaining nutrients |
ileocecal | the ____________ valve separates the small and large intestine |
internal | the _________ anal sphincter - smooth muscle - involuntary control |
external | the _________ anal sphincter - skeletal muscle - voluntary control |