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MCATBio Renal+Digest

TermDefinition
colon this excretory organ reabsorbs water and eliminates solid waste (material eaten but NOT absorbed in blood)
liver this excretory organ eliminates hydrophobic waste (fat, cholesterol) --> material eaten AND absorbed in blood BUT too hydrophobic to dissolve in plasma
kidney this excretory organ eliminates hydrophilic waste, which includes material eaten, absorbed and dissolved in blood, and filtered out of plasma
kidney this excretory organ regulates BP ion balance, water balance, pH; secretes erythropoietin, performs small amount gluconeogenesis; responsible for activation of vitamin K
erythropoietin secretion of ______________ by the kidneys increases RBC formation
adrenal ___________ glands sit on top of the kidneys but are not apart of the renal system
internal __________ urinary sphincter is made up of smooth muscle; involuntary control
external ___________ urinary sphincter is made up of skeletal muscle; voluntary control
ureter the ________ connects the kidney to the bladder
cortex the outer layer of the kidney
medulla the inner layer of the kidney
nephron functional unit of a kidney
renal pelvis the connecting point between the medulla and the ureter; once urine reaches this point, no further modifications are made
increases osmolarity _____________ as you move from cortex to medulla because solute concentration is increasing
in, out water moves ____ to the medulla and ____ of the nephron in the medulla
loops of henle these are structures of nephrons - can be long or short
long (long/short) loops of henle perform water retention better and are found in animals such as camels and other desert animals
short (long/short) loops of henle don't enter as far into the nephron so they don't perform water retention the best and are found in freshwater animals such as manatees
urine nephrons make _______
filtration - first step in process to produce urine - moves a substance (blood plasma) across a membrane (capillary wall) using pressure (BP)
plasma, proteins capillary wall membranes are fenestrated: this allows the diffusion of primarily water and things found in _______: the membrane allows the diffusion of these things EXCEPT ________ and large blood cells
reabsorption - second step in process to produce urine - moves a substance from the filtrate (sitting in the nephron) back into the blood - glucose, amino acids - water (based on the body's needs)
secretion - third step in process to produce urine - moves a substance from the blood back into the filtrate - drugs, toxins, creatine
afferent arterioles this group of vessels bring blood into the capsule of the nephron
efferent arterioles this group of vessels bring blood away from the capsule of the nephron
glomerulus a network of capillaries in the capsule of the nephron where filtration occurs
dilate, constrict you want more blood going into capsule than leaving ∴ afferent arterioles should _________ efferent arterioles should _________
bowman's capsule the first part of the nephron in which filtration takes place (full name)
proximal convoluted tubule the first part of the tubule (PCT) closest to the capsule in which reabsorption and secretion takes place; mostly unregulated
reabsorbed at the proximal convoluted tubule - glucose, amino acids, H+, and H20 are _____________ (--> medulla)
loop of henle this structure of the nephron directly follows the proximal tubule - two parts: descending and ascending limb - two parts have opposite permeabilities to water and sodium
descending, out in the ___________________ limb of the loop of henle - high permeability to H2O --> H2O diffuses ______ the nephron - impermeable to Na+
ascending, out in the ___________________ limb of the loop of henle - impermeable to water - high permeability to Na --> Na+ diffuses ______ the nephron
distal convoluted tubule the second part of the tubule (DCT) farthest from the capsule has specialized reabsorption and secretion due to high regulation by the hormone, aldosterone
aldosterone _____________ increases Na+ reabsorption and increases K+ secretion in the distal convoluted tubule of the nephron in the kidney
collecting duct this part comes directly after the nephron and regulates H2O reabsorption via aquaporin channels
ADH the permeability of aquaporin channels is dependent on whether ______ is present
open when ADH is present, aquaporins will _____ and H2O will be reabsorbed back into the blood stream
vasa vecta capillaries that wrap around the loop of henle
capillaries H2O leaving the loop of henle is taken up by ___________ called the vasa vecta
efferent H2O taken up by the vasa vecta transported to the _________ arteries
decreases as urine volume increases --> urine concentration __________
decreases as urine volume increases --> blood volume ____________
drop a (drop/raise) in blood pressure is more deadly
renin when blood pressure drops, kidneys secrete _______
angiotensin I when kidney secrete renin, angiotensinogen is converted to ___________ __
ACE angiotensin I is converted into angiotensin II with the help of __________
vasoconstriction angiotensin II causes systemic _______________ which increases BP
decreases systemic vasoconstriction (caused by angiotensin II) causes the afferent arteriole to constrict, which ____________ blood flow into the nephron
aldosterone, decreases angiotensin II increases ____________ release from the kidneys --> increases Na+ reabsorption --> increases blood osmolarity --> _______ blood volume
ADH, increases low blood volume due to high blood osmolarity triggers _____ to be released to compensate ---> _________ water reabsorption --> increases blood volume --> increases BP
juxtaglomerular apparatus connecting point between the afferent arteriole and the distal convoluted tubule; JGA
baroreceptors the side of the JGA closest to the afferent arteriole has lots of ____________ which detect pressure changes
chemoreceptors the side of the JGA closest to the distal convoluted tubule, there are lots of ____________ which detect changes in concentration (osmolarity)
decreases, renin, increase when filtrate osmolarity __________, the JGA closest to the DCT stimulates the afferent arterioles to release ________ and directly dilates the afferent arterioles --> _________ filtration rate through the kidney
ANP when BP increases, the atria stretch, and the R. atrium release ________
vasodilation, inhibits ANP causes ___________ in the muscles of the arterial walls and _____________ renin release --> decreases BP
slow renal regulation of blood pH is (slow/fast)
fast respiratory regulation of blood pH is (slow/fast)
carbonic anhydrase CO2 + H2O is converted into H2CO3 by ___________ ________, which is immediately converted into H+ and HCO3-
acidic the kidneys primarily secrete H+ and reabsorb HCO3-, which makes urine ____________
alimentary canal long muscular tube that goes from mouth to anus
bile the liver makes _________ which is amphipathic and facilitates fat digestion
bile _____________ surrounds smaller fat globules and allows digestive enzymes to access the fat and further break it down
gallbladder stores and concentrates bile; you can live without this but will need a low fat diet
glucose the endocrine part of the pancreas regulates blood _______ levels via insulin and glucagon (endocrine role)
digestive, secretes the pancreas is the main source of many _________ enzymes and ________ HCO3- to neutralize the acidic pH of the stomach
narrows when the circular muscles of the alimentary canal wall contracts --> the tube __________
shortens when the longitudinal muscles of the alimentary canal wall contracts --> the tube _______
wave of peristalsis circular and longitudinal muscles work together by contracting to push bolus of food down the canal
mouth the function of the __________ is to grind food, moisten food, and begin starch + lipid digestion
saliva the exocrine glands of the mouth secrete _______, which is composed mainly of water, as well as lysozymes, amylases, and lingual lipases
esophagus the function of the ___________ is to act as a tube that carries food down to the stomach
smooth the esophagus starts as skeletal muscle and becomes __________ muscle
cardiac sphincter this structure of the esophagus prevents the reflux of stomach contents; aka. the lower esophageal sphincter
mucus the exocrine gland in the esophagus releases ________
zymogen this refers to an inactive, digest enzyme
stomach the function of the __________ actually involves very little digestion and absorption and primarily acts as a tank for food, but does some acid hydrolysis
gastric the stomach contains _________ glands, which include cheif, parietal, and mucus cells, which are examples of exocrine glands
chief __________ cells make pepsinogen
parietal __________ cells secrete HCl to make the environment of the stomach acidic
mucus __________ cells secrete mucus which protects the stomach cells (lining)
activated pepsinogen is _________ when it comes in contact with acid in order to make pepsin
G-cells the endocrine glands of the stomach include __________, which secrete gastrin, activate gastrin glands, and is involved with negative feedback via acid
small intestine this part of the digestive system is where virtually all digestion and absorption occurs; 3 regions: duodenum --> jejunum --> ileum
enterokinase, trypsin ______________ is an exocrine enzyme in the small intestine that activates one of the pancreatic zymogens, trypsinogen, which when activated becomes ___________, which sends off a cascade of activating other pancreatic enzymes
brush border __________ ____________ enzymes create monomers for absorption and is the final step in digestion
enterogastrone this is an endocrine hormone in the small intestine that slows down stomach emptying and motility
CCK this is an endocrine hormone that stimulates bile release
secretin this is an endocrine hormone that stimulates the release of HCO3-
large intestine this part of the digestive system mainly involves reabsorption of water and storage of feces
bacteria ________ in the large intestine secrete vitamin K which results in blood clotting; eats up any remaining nutrients
ileocecal the ____________ valve separates the small and large intestine
internal the _________ anal sphincter - smooth muscle - involuntary control
external the _________ anal sphincter - skeletal muscle - voluntary control
Created by: coletty218
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