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ARRT Review

Radiation Safety Part 1 - Biological Aspects of Radiation

QuestionAnswer
What type of dose-response relationship is characterized by an early response to a high-dose exposure? Deterministic or non-stochastic
What type of dose-response relationship is characterized by a late-response to a low-dose relationship? Stochastic or probabilistic
What is described as a measure of the rate at which energy is transferred from ionizing radiation to soft tissue? LET (linear energy transfer
What are two examples of radiation-induced conditions that follow a linear nonthreshold dose-response relationship? Genetic effects, radiation -induced cancer,, leukemia
Skin effects that result from fluoroscopic exposure follow what type of dose-response relationship? Non linear(Sigmoid), threshold dose response curve
What type of effects are described as "those biologic somatic effects of ionizing radiation that exhibit a threshold dose below which the effect doses not normally occur and above which the severity of the biologic damage increases?? Nonstochastic (deterministic) effects
What is the cellular component having the greatest radiobiological significance? DNA
What effect does the presence of oxygen have on radiosensitivity? Oxygen Increases Radiosensitivity
Which of the following ionizing radiations has the highest LET? Alpha, Beta, Gamma, X-ray Alpha
What term is used to describe the human sequence of events following high-level radiation exposure, and leading to death in a short time? Acute Radiation Syndrome
List three major types of acute radiation syndrome. Hematological (Hematopoietic), Gastrointestinal, and CNS
Which of the three types of ARS requires the least amount of ionizing radiation dose to occur? Hematological (Hematopoietic)
What are the radiation weighing factors of x-ray, gamma and Alpha? 1, 1, 20
Describe the energy and LET of occupational radiation. Low energy and low LET
Give two examples of common local tissues that can be affected by ionization radiation Skin, lens of eye
Erythema can be an effect of excessive ionizing radiation exposure to what body part? Skin
List the following in order of decreasing radiosensitivity: skin, lungs, gonads, liver Gonads, lungs, liver, skin
Radiation -induced biologic damage organisms is termed ____ effects Somatic
Nonstochastic effects may also be referred to as _____ effects Deterministic
NCRP limit for Occupational Dose for Lens of eye 150 msv
NCRP limit for Occupational Dose for Gonads - Somatic effects 50 msv
NCRP limit for Occupational Dose for Thyroid (Deterministic effects) 500 msv
NCRP limit for Occupational Dose for Embryo/Fetus monthly .5 msv
NCRP limit for Occupational Dose for Embryo/Fetus Gestation 5 msv
NCRP limit for Public dose of lens of eye (Deterministic) 15 msv
NCRP limit for Public dose for infrequent exposures - Somatic effects 5 msv
NCRP limit for Public Dose for frequent exposures - Somatic effects 1 msv
NCRP limit for Occupational Dose for Deterministic effects - hands, feet, arms 500 msv
NCRP limit for Public Dose for Deterministic effects - hands, feet, arms 50 msv
Somatic effects that occur within minutes, hours, days, or weeks after the initial irradiation are termed ____ early, short term effects
What is the minimum radiation dose required in order for ARS to occur? 1 gy
The latent period in the ARS decreases as radiation exposure ______________ increases
How does oxygenation affect cell/tissue radiosensitivity? The presence of oxygen increases cell/tissue radiosensitivty
What is LD 50/30 for adult humans? 3 to 4 gy
A dose of 2 gy to the skin can cause a radiation induced reddening termed _____ erythema
Ionizing radiation induced hair loss is termed _______ epilation or alopecia
What is the name of the particularly radiosensitive sex cell? Spermatogonia
What is the target organ believed responsible for radiation induced leukemia? Bone marrow
What radiation exposure dose to the ovaries will result in temporary infertility? 2 gy
In which portion of the pregnancy is the embryo/fetus most radiosensitive? 1st trimester
What is defined as " the estimated dose to the gonads that , if received by the total population gene pool, would produce the total genetic effect on the population as the sum of the individual doses actually received"? GSD - Genetic Significant Dose
What are the three guidelines for determining when the gonads should be sheilded? When gonads are within 5cm of collimated primary beam, when patient is of reproducible age, and when clinical exam allows
What three parts of the body should be shielded from the useful beam whenever possible? the lens of the eye, the breasts, and gonads
1 mm lead flat shield is used to shield female gonads and can reduce dose by ______ % 50
1 mm lead flat shield is used to shield male gonads and can reduce dose by ______ % 90-95
List 4 types of late effects of ionizing radiation exposure Carcinogenesis, Cataractogenesis, embryological effects, and lifespan shortening
What skin layer is the most sensitive? Basal cell
What are the two most common interactions between x-ray photons and tissue cells? Compton and photoelectric
Which of the major interactions between x-ray photons and tissue cells occurs with high energy photons?` Compton
Which of the major interactions between x-ray photons and tissue cells most likely occur with high atomic number?` Photoelectric
Which of the major interactions between x-ray photons and tissue cells results in total absorption of the incident photon?` Photoelectric
Which of the major interactions between x-ray photons and tissue cells is a major contributor to patient dose? Photoelectric
Which of the major interactions between x-ray photons and tissue cells predominates in the diagnostic x-ray range? Compton
Which of the major interactions between x-ray photons and tissue cells is responsible for scattered radiation fog? Compton
Which of the major interactions between x-ray photons and tissue cells poses a radiation hazard to personnel? Compton
Which interaction between x-ray photons and matter involves an outer shell electron and only partial transfer of energy? Compton
Which interaction between x-ray photons and matter involves a low energy incident photon? Photoelectric
Which interaction between x-ray photons and matter is most damaging to the diagnostic image? Compton
Which interaction between x-ray photons and matter involves the greatest patient dose? Photoelectric
Which interaction between x-ray photons and matter occurs the least often and is the only interaction that does not cause ionization? Coherent
Which interaction between x-ray photons and matter involves a recoil electron? Compton
Which interaction between x-ray photons and matters most likely is to occur in a high density tissues like bone? Photoelectric
Which interaction between x-ray photons and matter is the most potential radiation hazard to personnel? Compton
Which interaction between x-ray photons and matter produces a characteristic ray? Photoelectric
Which interaction between x-ray photons and matter is most likely to produce short-scale contrast? Photoelectric
What component of personal dosimeters functions to evaluate radiation quality? Filters (Aluminum, Copper, Tin)
Which of the following three types of dosimeters is the most sensitive? TLD, or OSL? OSL
What are the two weighing factors that are used to determine the Sievert? WT (tissue) and WR (Radiation type)
Are radiation induced cataracts considered early or late effects? late
What would an early effect(s) be considered from the following: leukopenia, nausea, or leukemia leukopenia (decreased white blood cells), nausea
Created by: rcberger06
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