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Lecture 19
Chapter 12 pt.1
| Question | Answer |
|---|---|
| What are the key features of signal transduction? | Specificity Amplification Desensitization/adaption Integration |
| Desensitization/adaption occurs | When the response is denied although there is still a signal |
| What happens in specificity? | The signal molecule binds to a specific site producing a receptor; measure of which we can determine the ligand. |
| Amplification is | When the enzymes activate enzymes which causes the number of affected molecules to increase in an enzyme cascade |
| Signal integration are | Several signals that are given at once, all of which impinge on their receptors. These signals can then b combined from these receptors. |
| Intracellular ligands are________ and can enter the nucleus ________ | non-polar; directly |
| How are secondary messenger pathways created by cell surface receptors? | Polar ligands |
| What is Tyr (tyrosine) derived? What simulates the activity and what inhibits the activity? | Epinepherine Agonists, antagonists |
| How are the tyr (tyrosine) constants controlled, in both cases? What does the control allow you to do? | Lower Kd What, when, and how much of a response is given. |
| What do G proteins cycle through? | GDP-bound (on) and GTP-bound (off) |
| Phospoholipase C ____ &______ IP3 | cleaves and releases |
Created by:
hilarye
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