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Lecture 16

Chapter 11 pt.1

QuestionAnswer
What are membranes composed of, and how are they arranged? Proteins & Lipids Asymmetrically
Glyerophospholipids are composed of what type of linkage? What type of linkage forms a sphingolipid? Glyerophospholipid=Ester Sphingolipid=Amide
Proteins have sidedness, although AA's not always found equally in all layers of the bilayer. Which proteins are found inside, which outside? Are proteins hydrophobic or hydrophillic inside, and what is the charge? Histidine (His/H), Arginine (Arg/R), Lysine (Lys, K) inside Aspartic Acid (Asp/D), Glutamic Acid (Glu, E) outside Hydrophobic, Phenylalanine (Phe/F) Polar uncharged on either side
Which proteins are found at the leaflets? Tryptophan (Trp/W), Tyrosine (Tyr/Y)
How manny TM (transmembranes) does bacteriorhodopsin contain? What else does the bacteriorhodopsin contain? How is it anchored? 7 TM helices and contains retinal Lipids anchor the bacteriohodopsin
What delta G indicates hydrophobic? Hydrophilic? +=Hydrophobic, -=hydrophilic
What are the delta G's for Phe, Ser, Glu? +, -, -
How are proteins anchored to the hydrophobic region? Proteins are anchored by lipids
What allows a polar solute across the membrane? Porins
Created by: hilarye
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