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rad bio ch 36

radiation biology ch 36

QuestionAnswer
Stochastic effects are late effects of radiation
What type of curve do radiation protection guidelines follow? linear nonthreshold
Where does radiation induced cataracts occur? the posterior pole of the lens
What effets do high LET radiation have on the eye? will cause cataracts 100% of the time
What type of curve do cataracts follow? nonlinear threshold
At worst, what amount of lifespan shortening can be expected from radiation exposure? 10 days per rad
What is the formula for relative risk? observed cases/expected cases
What type of curve does leukemia follow? linear nonthreshold
What is the latent period for leukemia? 4-7 years
What is the at risk period for leukemia? 20 years
What is the latent period for cataracts? 5-30 years
What was the An Arbor series? peds 20-30 rad to the thymus, 1940’s-50’s late effects thyroid cancer
What was the Rochester Series? peds 300 rad to thymus, 1940’s-50’s late effect thyroid cancer
What was the Rongelap Atoll case? atomic bomb testing fallout exposure. 1200 rad to thyroid
What type of curve does thyroid cancer follow? linear nonthreshold
What is the half life of radium? 1620 years
How much radium was the maximum ingested by the watch dial painters? 500 Gy (50,000 rad)
What type of curve do skin cancers follow? threshold
What is the latent period for skin cancers? 5-10 years
What is the relative risk for rad techs and breast cancer? 1.13
BEIR Biologic Effectiveness of Ionizing Radiation
What is the most radiosensitive phase for the fetus? 1st trimester (weeks 2-10)
What is the most radiorestistant phase for the fetus? weeks 0-2
How much does 10 rad increase the risk of congenital abnormalities? 1% (norm. is 5%)
How much does 10 rad increase the risk of spontaneous abortion? .1% (norm 25%)
What is the period of major organogenesis for a fetus? weeks 2-10
When might DNA damage occur to the fetus with radiation exposure? weeks 2-10
when does skeletal development occur for the fetus? weeks 2-6
when does cognitive development occur for the fetus? weeks 6-10
how much does 10 rad increase the likeliness of mental retardation? .5% (norm 6%)
what is the doubling dose for humans? 50-250 rad
at what exposure level are abnormalities with pregnancy increased, potentially leading to a therapeutic abortion? 20-25 rad
Created by: annaluz87 on 2009-03-23



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