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AIDS
AIDS OT
| AIDS | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
| Risk factor | sexual contact with infected person | parenteral exposure to infected blood by transfusion or needle sharing | perinatal exposure | asymptomatic for 10 yrs | (blank) | (blank) |
| systemic complaints | fever and night sweats | weight loss | anorexia | (blank) | (blank) | (blank) |
| Sinopulmonary disease | pneumonia | infections with mycobacterium tuberculosis | interstitial infections ( due to kaposis sarcoma, non-hodgkins lymphoma) | sinusitis | (blank) | (blank) |
| CNS diseases | intracerebral space occupying leisions( taxoplasmosis, lymphoma, bacterial abscess, cryptococcomas, tuberculoma, nocardia leision, | encephalopathy ( aids dementia complex) | meningitis | spinal chord problems ( leg weakness, incontinence, spastic parapareisis) | (blank) | (blank) |
| PNS problems | sensory neuropathys | mono or polyneuropathy | (blank) | (blank) | (blank) | (blank) |
| rhumatologic manifistations | arthritis ( involving large joints) | sicca syndrome | psoriatic arthritis | (blank) | (blank) | (blank) |
| myopathies | proximal muscle weakness | muscle tenderness | (blank) | (blank) | (blank) | (blank) |
| visual changes | cytomegalovirus retinitis (eye herpes) | cotton-wool spots | retinal infections | (blank) | (blank) | (blank) |
| oral leisions | oral candidiasis | hairy leukoplakia (epstein-barr) | angular cheilitis ( candida infections) | gingival disease | aphthous ulcers | (blank) |
| GIT manifistation | candidal esophogitis | hepatic disorder | biliary tract disease ( acalculous cholecystisis, sclerosing cholangitis, papillary stenosis) | enterocolitis ( bacteria, viruses, protozoa) | (blank) | (blank) |
| endocrinologic manifistation | adrenal insufficiency | high levels of tryodithorine T3 tryoxineT4 and tbg | (blank) | (blank) | (blank) | (blank) |
| Skin manifistation | vesicular eruptions ( herpes simplex and zoster) | spreading leisions | folliculitis, furuncles, bullus impetigo | rashes in inguinal region | sborrheric dermititis, psoriasis | xerosis with sever pruritis, red and purple paulesaposi's sarcoma |
| gynecological manifistations | vagina candidiasis | cervical dysplasia | cervical neoplasia | pelvic inflammatory disease | (blank) | (blank) |
| HIV- related malignancys | Kaposi's Sarcoma | non-Hodgkins Lymphoma | primary lymphoma of brain | invasive cervical carcinoma | (blank) | (blank) |
| Diagnosis | screening seralogic test- ELISA | confirmatory test- Western Blot | Molecular Biology technique- polymerase chain reaction | core protein antigen determination (p24 antigen) | Laboratory markers (absolute CD4 lymphocyte count, viral load test, beta-2 microglobulin determination | (blank) |
| Treatment | AZT and DDI | Immune modulators and cytokines (interferon Beta and interleukin 2) | granulocyte colony stimulating factor | erythropoietin | prophylaxis for opportunistic infections | (blank) |
| prophylaxis | for PCP (trymethoprim, aerosol penta, dapsone) | myobacterium avium intracellular infection ( clarithromyacin, rifabutin) | (blank) | (blank) | (blank) | (blank) |
| SIDE EFFECTS of AZD and Tx | bone marrow supression , decrease in RBC results in anemia, decrease in wbc more sucessptible to infection and no platelet synthesis | USE GMSF to increase WBC | blood transfusion | erythropoetin to cure anemia and stimulate RBC | other SE include transiet mayalga- muscle pain that comes and goes, fatigue, and headach | (blank) |
| EFFECTS of DDI | pancreatitis - inflammation of pancreas( problems digesting fats) (vitamin adek defficient) | peripheral neurop-parasthesia ( pins and needles) occurse 9 moths after using DDI | (blank) | (blank) | (blank) | (blank) |
Created by:
natkat
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