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Biochem Test 2

More BPG pushes O2 binding curve ... right, by stabilizing low saturation
More CO2 pushes O2 binding curve ... right, by forming carbonic acid and H+ binds to Hb
High altitude pushes O2 binding curve ... right, by increasing BPG
Bohr Effect? decreased affinity for O2 as pH drops, right shift
Less BPG pushes O2 binding curve ... left, by destabilizing low saturation
Less CO2 pushes O2 binding curve ... left, by removing carbonic acid and H+
Low altitude pushes O2 binding curve ... left, by decreasing BPG
6M Guanidine dissociates oligomers by causes random cysteine binding
NaCL dissociates oligomers by disrupting ionic interactions
low temperature dissociates oligomers by lowering entropy
beta mercaptaethonal dissociates oligomers by cleaves disulfide bonds
low pH dissociates oligomers by protonating everything, reducing favorable and increasing nonfavorable interactions
detergents dissociates oligomers by solubilizing hydrophobic regions
protein disulfide isomerase sends proteins... secretion outside of the cells
Created by: sschooley