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NMT Review Test 2
Steve's Review Exam 2 Part 2
| Question | Answer |
|---|---|
| Which of the following radiopharmaceuticals should be prepared if a renal function study is being performed to determine the glomerular filtration rate: A)99mTc-gluceptate B)99mTc-mertiatide C)99mTc-pentetate D)99mTc-succimer | C)99mTc-pentetate is the renal agent used to determine glomerular filtration rate because it is handled by the kidneys solely by glomerular filtration. It is neither bound to protein nor secreted by the renal tubules as are other renal agents. |
| Aluminum is a chemical impurity and not subject to regulations by the NRC. True or False? | True |
| Heating is required during the preparation of all of the following 99mTc-labeled radiopharmaceuticals except: A)bicisate B)mertiatide C)sestamibi D)sulfur colloid | A)99mTc-bicisate requires a 30 minute incubation at room temperature. For the other radiopharmaceuticals listed, heating is required for the preparation. |
| To calculate the yield of a 99Mo/99mTc generator, the first step to be performed is what? | Determine the time elapsed between calibration of the 99Mo activity and generator elution. |
| What is the R(f) value of hydrolyzed-reduced 99mTc if the solvent front is 12.6cm from the origin: Hydrolyzed-reduced 99mTc is 2.5cm from origin; 99mTc-pertechnetate is 12.6cm from origin. | R(f)=0.20 R(f)value is the distance traveled by a given RC component compared with the solvent front. R(f)= dist. from Origin to RC component/dist. from Origin to solvent front. R(f) value for hydrolyzed reduced Tc99m is: R(f) = 2.5cm/12.6= 0.20 |
| All of the following units are expressions of radiopharmaceutical specific activity except: A)uCi/mg B)kBq/mL C)Ci/g D)MBq/mole | B)kBq/mL. Specific activity is defined as the amount of radioactivity per unit mass of a radionuclide or labeled compound and is expressed in units of radioactivity per mass. |
| A tech needs 1mCi 111In at 0900 on May 18. What volume is required to obtain the necessary activity on May 18 using the following information: Total act=3.0mCi; Total vol=3.0mL; Assay=1200, May 21; DF=0.480 | 0.48mL |
| If 25uCi of a radiopharmaceutical are to be administered for each kilogram of body weight, approximately how much activity should be administered to a child weighing 15.5kg: A)852uCi B)0.39mCi C)0.85mCi D)1.6mCi | B)0.39mCi |
| For labeling RBC's, the prescribed dosage of 99mTc-pertechnetate is 925MBq(+-)10%. Which dose calibrator reading verifies the prescribed activity was dispensed: A)21mCi B)28mCi C)20mCi D)25.5mCi | D)25.5mCi. 925MBq=25mCi |
| The USP 26 limit is ___ Al/mL 99mTc for fission-produced 99Mo: A)10mg B)10ug C)15mg D)15ug | B)10ug |
| Venipuncture materials labeled with which of the following expiration dates may be used safely on Aug 10: A)July 31 B)Aug 31 C)Sept 30 D)Oct 1 | B,C,D. Materials that have passed their expiration date should not be used with patients. In the case of venipuncture materials, the sterility of the materials may be compromised. |
| According to NRC, all the following information must appear in the record of 99Mo concentration measurements except: A)ratio of 99Mo to 99mTc activities B)name of individual making the measurement C)dose calibrator make and model D)time and date | C)Dose calibrator make and model. Records of 99Mo concentration measurements must include the other information. |
| According to NRC, a written directive must be prepared for administration of which radiopharmaceuticals: A)1mCi 111In-oxine B)5mCi 131I-sodium iodide C)10mCi 67Ga-citrate D)30mCi 99mTc-sestamibi | B) According to the NRC, a written directive is required for any dosage of 131I-sodium iodide grater than 30uCi or for any therapy dosage of an unsealed by-product material. |
| If 99mTc eluate needs to be diluted to prepare other 99mTc-labeled products, the correct diluent is: A)sterile saline containing 0.2% thiosulfate B)preservative free isotonic saline C)bacteriostatic saline D)distilled water | B) If 99Tc eluate needs to be diluted to prepare other 99mTc-labeled products, the correct diluent is preservative-free isotonic saline. |
| A unit dose of 67Ga-citrate is calibrated for 0800 on July 9 contains 5mCi in 2.6mL. If 3mCi are needed on July 10 at 0800, what volume should be retained in the syringe. DF=0.808 A)1.5mL B)1.9mL C)1.1mL | B)1.9mL |
| If a 2.5Ci 99Mo/99mTc generator is estimated to contain 268mCi of 99mTc-pertechnetate, but 198mCi are eluted, what is the approximate elution efficiency: A)74% B)26% C)11% D)8% | A)74% |
| The USP 26 limit for 99Mo breakthrough, the 99Mo contamination in the 99mTc-eluate, is ___99Mo/mCi99mTc per administered dosage at time of administration: A)0.10uCi B)0.15uCi C)0.20uCi D)0.10mCi | B)0.15uCi |
| Which of the following federal agencies regulates the packaging and transport of radioactive materials: A)DOT B)EPA C)FDA D)NRC | A)DOT. The U.S. Department of Transportation regulates the packaging and transport of radioactive materials. The NRC regulations follow DOT requirements. |
| Which of the following exposure rates indicates a package must be labeled with a category 11 DOT label: A)52mR/hr surface 2.2mR/hr @ 1 meter B)35mR/hr surface 1.0mR/hr @ 1 meter C)65mR/hr surface 5.5mR/hr @ 1 meter | B) Category 1 (white)= <0.5 surface, no detectable radiation @ 1 meter Category 11 (yellow)= <50 surface, 1.0 or less @ 1 meter Category 111 (yellow)= <200 surface, 10 or less @ 1 meter |
| When RBC's are labeled with 99mTc using the in vivo method, what order are the reagents(stannous pyrophoshate and 99mTc-pertechnetate) injected? | Reconstructed stannous pyrophosphate must be administered first. This step, sometimes referred to as "pretinning," permits 99mTc-pertechnetate to enter the red blood cells. |
| If the radiation intensity of a point source at 0.5 m measures 36mR/hr, at what distance will the intensity be halved? | 0.7m |
| If the HVL of 60Co in lead is 1.25cm, what percentage of 60Co photons is absorbed from a 60Co source shielded with 2.5cm of lead? | 75% |
| According to the NRC, a written directive is required for the administration of all the following radiopharmaceuticals except: A)25mCi 131I-sodium iodide B)20mCi 18F-FDG C)15mCi 32P-sodium phosphate D)10mCi 89Sr-chloride | B) 20mCi 18F-FDG |
| According to NRC regulations, the annual occupational dose limit to any organ or tissue other than the eye is: A)50mSv B)5mSv C)15rem D)50rem | D)50rem or 500mSv. |
| According to NRC regulations, which of the following can't be disposed of in the sewage system: A)diaper of a child who has received 67Ga B)feces from a patient who received 131I therapy C)unused 123I sodium iodide capsules D)urine from a renal test | C)unused 123I sodium iodide capsules. Only patient excreta are exempt from any limits when discarded into the sewage system. |
| In performing a room survey with an end-window GM counter, the tech should first: A)measure the room background B)perform a battery test on the counter C)perform a wipe test D)measure designated areas on the survey diagram | B) To ensure that the batteries are functional, a battery check should be performed immediately before taking any measurements with a survey meter. |
| Normal values for a solid Gastric emptying study is: A)30-45min B)45-60min C)50 to 80min D)60-80min | C) Normal values are 50-80min for solid meals and 10-15min for liquid meals. |
| A container of 131I measures 0.08mR/h, and room background measures 0.07mR/hr. The tech should next: A)obliterate any radiation symbols and dispose of the container in regular trash B)dispose of the container as radioactive waste | A) The exposure rate of the packing material is approximately the same as room background, so the carton may be disposed of in the regular trash after any radiation symbols are removed or obliterated. |
| According to NRC regulations, in what areas can radioxenon be administered: A)in any room that can be closed off with doors B)only in rooms that have xenon alarm systems C)only in imaging rooms that can be negatively pressurized | C)only in imaging rooms that can be negatively pressurized. |
| When can a decay factor be used to calibrate a unit dosage in place of measuring the dosage in a dose calibrator: A)only if a unit dosage was not manipulated after preparation and calibration B)only if the dosage contains less than 1mCi activity | A)only if a unit dosage was not manipulated after preparation and calibration. |
| A patient received 5mCi 131I-sodium iodide for treatment of hyperthyroidism. The patient should adhere to all instructions except: A)minimize close contact with others B)remain home at lest 30 days C)drink plenty of fluid D)wash hands after using toilet | B)patients should be given instructions to follow for 3 to 7 days that will minimize spread of contamination and radiation exposure to others. |
| After a 99mTc spill, decontamination procedures have not been able to remove all of the spilled material. If the current exposure rate is 32mR/hr, how long will it take for the exposure rate to drop to 2mR/hr? | 24hr. |
| If a patient is hospitalized in isolation after receiving a high activity of 131I, which sign must be placed on the door: A)authorized personnel only B)sign noting the length of time a visitor may stay in the room C)reverse isolation procedures required | B) If a person is hospitalized after administration of a therapeutic dosage of 131I, the door of the room must have signage that indicates the length of time a visitor may stay. |
| How soon after a medical event has occurred must the NRC be notified: A)telephone notification no later than the following calendar day B)telephone notification within 72h C)written report within 5 regular workdays D)written report within 30 days | A)NRC regulations state that the NRC Operations Center must be notified of a medical event (error) (misadministration) no later than the next calendar day. |
| According to NRC, written instructions must be provided to a patient who has received radionuclide therapy when: A)female of childbearing age B)every patient must receive instructions C)another individual may receive exposure greater than 0.1rem | C)NRC regulations state that written precautions must be provided to the patient or the patient's parent or guardian if any individual is likely to exceed 0.1rem (1mSv) exposure from the therapy patient. |
| Which of the statements about the shielding method of performing a dose calibrator linearity test is true: A)when the shields are first used, the decay method must be used to confirm accuracy B)a different source activity is required for each shield | A)to ensure that the shields will give accurate results, the decay method must be performed at the same time the shields are first used. |
| The NRC requires that dose calibrators be tested for proper functioning according to nationally recognized standards. The standard of practice requires the measured value to be within (+-) __% of the calculated value. A)10 B)15 C)20 D)5 | A)10% |
| Full width at half maximum(FWHM) is defined as the width of the photopeak, expressed in keV, at one-half of the maximum or peak counts. True or False? | True |
| To perform a constancy test on a dose calibrator, the best choice of radionuclide settings on which to count the reference standard would include: A)125I, 123I, 131I B)125I, 57Co, 137Cs C)99mTc, 201Tl, 123I D)57Co, I131, 137Cs | C)After the long-lived reference is read on its setting, the same source should be used to obtain a reading on each commonly used radionuclide setting. |
| The two most commonly used radiopharmaceuticals for GI bleeding detection are? | 99mTc-SC and 99mTc-RBC's. |
| The standard of practice for performing a dose calibrator accuracy test calls for the use of how many long-lived reference sources: A)1 B)2 C)3 D)4 | B)the standard of practice calls for the use of at least two long-lived reference sources. |
| Which of the following filters is a high-pass filter: A)Butterworth B)Hanning C)Parzen D)Ramp | D)Ramp. The ramp filter is a high-pass filter, that is, it permits high frequencies to pass through while altering the lower frequencies. The other filters listed are low-pass filters used to eliminate noise. |
| In quantitating scintillation camera detector uniformity, the central FOV is defined as the diameter of the useful FOV times: A)0.75 B)0.5 C)0.33 D)0.25 | A)0.75 The UFOV is first determined by measuring the diameter of the largest area that can be inscribed within the collimated FOV. Then, the CFOV is defined as a circle with a diameter that is 75% of the UFOV diameter. |
| When the heart rate is 95bpm, what is the length of an average R-R interval: A)0.5sec B)0.63sec C)1sec D)1.6sec | B)0.63sec 60sec/95bpm |
| To perform pixel calibration, 2 capillary sources are placed on the camera surface 15cm apart. From an image acquired using a 128x128 matrix, an activity profile is generated. If there are 45 pixels between the 2 activity peaks, the pixel size is? | For point source or line source method for pixel calibration: pixel size = distance between sources / number of pixels between activity profile peaks: 15 cm / 45 pixels = 0.33 cm |
| Coincidence loss is likely to occur when using a well counter if the: A)E of radionuclide is below 50keV B)E of radionuclide is above 300keV C)activity of the source is below 1uCi D)activity of the source is above 2mCi | D)With activities in the mCi range & sometimes lower, photons are striking the wellcounter crystal @ very short intervals. The instrument is in deadtime while many photons are interacting with the crystal. These photons won't be counted & therefore "lost" |
| To assure a max error of 2% at the 95% confidence level, all samples that are measured in a well counter should be counted for a time interval that produces at least: A)10,000counts B)5,000counts C)1,000counts D)500counts | A)10,000 counts: The 95% confidence level is most commonly used in nuclear medicine. % error = (2)(100%)/ square root N; @% = (2)(100) / square root N; (square root N)^2 = (200 /2)^2; N= 10,000 counts |
| A 137Cs source was originally calibrated to contain 200uCi on June 1, 1998. What would be the expected activity of the source on June 1, 2002? 2 year DF=0.955 | 182.4uCi. 0.955 x 0.955 x 200uCi = 182.4uCi |
| A 57Co source originally calibrated to contain 325.8uCi 35 days ago. If the source is measured today, the reading must fall within what range of activities to meet the accepted standard? DF=0.914 | 268.0-327.6uCi; 325.8uCi x 0.914 = 297.8 297.8 (+-) 10% is accepted standard |
| It has been determined that a correction factor of 1.15 must be used when a 5mL syringe containing about 25mCi is measured. If a unit dosage activity reads 26.2mCi, what is the true activity? | 30.1mCi 26.2mCi x 1.15 = 30.1mCi |
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