ClinChem2 Last test Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
What represents the 4 principal biological events governing drug dispersion? | 1. Absorption 2. Distribution 3. Biotransformation 4. excretion |
What analyte would be useful to measure in a patient taking a nephrotoxic drug? | creatinine |
First-pass effect occurs in which organ of the body? | Liver |
The major enzyme system that metabolizes a drug in phase a I-type reaction is ? | Apolipoprotein P450 |
A drug agonist is described as ? | a drug that binds to receptors and mimics the regulatory effects of the endogenous signalling compounds. |
When should a trough level for drug measurement be found? | Just before the next dose |
When the concentration of a drug, like digoxin, is measured by the most routinely used immunoassay, what is actually measured? | Total drug concentration |
Toxic levels of methotrexate may result in what? | Bone disease/marrow abnormalities |
Ethylene glycol metabolizes to what acid? | Oxalic acid |
What class of compounds may be included in drugs-of-abuse screening (DAU)? | Barbituates |
What is an example of a definitive or reference method that is suitable for confirming positive drugs-of-abuse testing (DAU)? | GCMS |
Toxic doses of acetominophen can cause serious damage to what organ in the body? | Liver |
Carbon monoxide affinity for hemoglobin is ? | 200-250 times greater than oxygen's affinity for hemoglobin. |
What statement provides an accurate description of drug screening methods? | They provide qualitative information on a particular class of drugs. |
Reyes syndrome is associated with what substance? | Salicylate/aspirin |
What blood group antigen is CA 19-9 derived from? | Le-a |
Alpha-fetoprotein is useful in detecting which carcinoma? | hepatocellular |
The biochemical marker CA 125 is expressed by what tissue? | epithelial cells of the ovaries |
Biomarkers designed with the prefix letters CA contain a significant amount of what compound? | Carbohydrate |
Diagnostic sensitivity represents what condition? | Positively (or positivity?) in disease |
Measuring serum levels of CA 15-3 is clinically useful for what reason? | Monitoring the clinical course of patients with metastatic breast cancer. |
Alpha-fetoprotein is a marker for what cancer? | hepatocellular carcinoma |
Cancer-antigen 125 (CA-125) is a marker for what cancer? | ovarian |
Carbohydrate Antigen 15-3 (CA 15-3) is a marker for what cancer? | breast |
Human epididymisprotein (HE4) is a specific marker for what cancer? | ovarian |
BRCA1 and BRCA2 are gene mutations associated with what cancer? | breast |
Carcinoembryonic Antigen (CEA) is a marker for what cancer? | colorectal (also lung, breast, and gastrointestinal tumors) |
CA 19-9 is a marker for what cancer? | pancreatic (LE-a-b- people do not express this marker) |
Human chorionic gonadotropin (HCG) is a marker for what cancer? | trophoblastic tumors (but not FDA approved) |
Prostate-specific antigen (PSA) is a marker for what cancer? | prostate (also BPH and prostatitis) |
PCA-3 is a specific marker for what cancer? | prostate (it stands for prostate cancer gene 3) |
Digoxin is what type of drug? | cardiac glycosides |
Quinidine, Procainamide, Dispyramide, are all what class of drugs? | antiarrythmics |
Vancomycin and aminoglycosides are both what type of drugs? | antibiotics |
Phenobarbital, Phenytoin, Carbamazepine, Ethosuximide, and Valproic acid are all what kind of drugs? | antiepileptic drugs |
Lithium, tricyclic antidepressants, clozapine, and olanzapine are all what kind of drugs? | psychoactive |
Cyclosporine, tacrolimus, sirolimus, and Mycophenolic acid are all which kind of drugs? | immunosuppressive |
Felbamate and Babapentin are both what kind of drugs? | 2nd generation antiepileptic drugs |
Methotrexate is what class of drugs? | antineoplastic |
Drug X has a half-life of 15 hours. When will the patient reach a steady state in the therapeutic range? Is it 1 day, 3 days, 5 days, or 7 days? | 5 days (since 4 is not an answer) |
The factor for figuring out the time needed to achieve a steady state is ? | 5-7 : use the factor that matches the choices given on the test : multiply the number of hours by the factor, then divide by 24 to find out how many days. |
If a patient has a renal insufficiency, would he reach the steady state sooner or later? | Sooner, because the kidneys would not remove the drug in the urine as quickly. |
Which is a faster means of drug absorption: IV or inhalation? | Both are about the same. |
The most common drug of abuse in the US is ? | Alcohol |
Don't forget to try the "Targets" button below to practice matching up tumor markers. | Just click on "targets" below. |
I have a medication matching test as well. | http://www.studystack.com/flashcards-1578487 |
Created by:
IsaacJ
Popular Chemistry sets