for immunology test
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| What complement compound is in both the classic and alternative pathway? | C3
🗑
|
||||
| What is the goal of complement? | lysis (or removal) of cells coated with specific antibody
🗑
|
||||
| What activates the alternative complement pathway? | c3b (coated pathogen)
🗑
|
||||
| Which complement protein acts as an opsonin | c3b- Bb-C3bP
🗑
|
||||
| What is cleaved by C3b-Bb | C3
🗑
|
||||
| What is the order of activation in the lectin activation pathway | MBL, c4, C2, C3
🗑
|
||||
| What is first cleaved by Clqrs in the classical pathway | c4
🗑
|
||||
| What initiates complement activation in the lectin pathway | Mannose binding Lectin
🗑
|
||||
| what is cleaved by c4b2a3b | c5
🗑
|
||||
| Which complement proteins are not used in the alternative pathway? | c1, c2, c4
🗑
|
||||
| deficiency in C2 would lead to what disease? | immune complex disease
🗑
|
||||
| What factors are only associated with the alternatice pathway? | factors B and D
🗑
|
||||
| what complement protein polymerizes to cause lysis of a foreign cell | C9 (last protein in attack complex)
🗑
|
||||
| The recognition unit in the classical complement pathway consists of what? | clqrs
🗑
|
||||
| Lack of complement inhibitor C1INH leads to | hereditary angiodema
🗑
|
||||
| what stabilizes C3 and C5 convertase in the alternative pathway? | properdin
🗑
|
||||
| what factor is the key intermediate in all pathways | c3
🗑
|
||||
| In the alternate pathway, factor B must bind to _____ to initiate the cascade | C3b
🗑
|
||||
| What must be associated with factor H to inactivate complement components? | factor 1
🗑
|
||||
| what factor helps dissociate C3b from RBC's | DAF (this doesn't happen in paroxysmal nocturnal hemoglobinuria)
🗑
|
||||
| What protein inhibits the classical pathway at the very beginning | C1INH
🗑
|
||||
| what is characteristic of complement proteins (what do they all do) | Complement proteins play a role in inflammatory response
🗑
|
||||
| which pathway is factor B in | alternative
🗑
|
||||
| Which pathway is properdin in | alternative
🗑
|
||||
| what pathway is C1, C4, C2 part of | classical
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
amandalk