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First AID Antiarrhythmic Drugs

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Question
Answer
Mnemonic to remember the antiarrhythmics   show
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General information about Class I Antiarrhythmics   show
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Drugs of Class IA   show
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General Mech of Class IA   show
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show Affect both atrial and ventricular arrhythmias, especially reentrant and ectopic supraventricular and ventricular tachycardia.  
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Causes cinchonism, thrombocytopenia, and torsades des pointes   show
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show Headache, tinnitus and dizziness  
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show Quinidine  
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show Procainamide  
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Can cause a reversible SLE-like syndrome   show
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SE common to all Class IA   show
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Drugs of Class IB   show
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General mechanism of Class IB drugs   show
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show Acute ventricular arrhythmias (esp post MI) and in digitalis-induced arrhythmias  
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show Local anesthetics - cause CNS stimulation/depression, cardiovascular depression  
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Drugs of Class IC   show
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General actions of Class IC   show
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show Useful in V-tachs that progress to VF and in intractable SVT. Also DOC for WPW.  
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Toxicity of Class IC   show
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show Class IA antiarrhythmics  
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show Class IB antiarrhythmics  
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Useful in V-tachs that progress to VF and in intractable SVT   show
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show Class IA = Increase AP duration. Class IB = Decrease AP duration, Class IC = don't effect AP duration  
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Area of heart affected by Class I antiarrhythmics   show
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Class II antiarrhythmics   show
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General actions of Class II   show
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Indications for Class II   show
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show Impotence, exacerbate asthma, AV block, may mask signs of hypoglycemia  
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CI of Beta blockers   show
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How to remember class III antiarrhythmics   show
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show Prolong Phase 3 w/o affecting Phase 0. Increase AP duration, Increase ERP, Increase QT interval. Use these when other antiarrhythmics fail  
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SE: Torsades des pointes, excessive B-block   show
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show All can cause torsades des pointes (b/c inc QT interval)  
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SE of Amiodarone:   show
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show Calcium channel blockers  
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General mech of Class IV   show
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General SE of Class IV   show
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show Adenosine  
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Depresses ectopic pacemakers, especially in digoxin toxicity   show
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Effective in torsades de pointes and digoxin toxicity   show
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Created by: tommyparisi