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Nucleotides and Nucleic Acids

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show adenosine  
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show uracil  
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show a deoxyribonucleotide has an —H instead of an —OH at C-2.  
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Which one of the following is TRUE of the pentoses found in nucleic acids?   show
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show join the 3' hydroxyl of one nucleotide to the 5' hydroxyl of the next.  
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The phosphodiester bond that joins adjacent nucleotides in DNA:   show
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show 3',5'-cAMP  
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show A) 2'- AMP B) 2',3'-cGMP C) 2'-CMP D) 3'-UMP  
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The DNA oligonucleotide abbreviated pATCGAC:   show
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show the nucleotide at the 5' end has a phosphate on its 5' hydroxyl.  
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The nucleic acid bases:   show
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Which of the following statements concerning the tautomeric forms of bases such as uracil is correct?   show
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In a double-stranded nucleic acid, cytosine typically base-pairs with:   show
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show The distance between the two glycosidic (base-sugar) bonds is the same in both base pairs, within a few tenths of an angstrom.  
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The experiment of Avery, MacLeod, and McCarty in which nonvirulent bacteria were made virulent by transformation was significant because it showed that:   show
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show A + G = T + C.  
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show absence of 2'-hydroxyl groups allows bases to lie perpendicular to the helical axis.  
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show the distance between two adjacent bases in one strand is about 3.4 Å.  
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Which of the following is NOT true of all naturally occurring DNA?   show
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show A) Deoxyribose units are connected by 3',5'-phosphodiester bonds. B) The amount of A always equals the amount of T. C) The two complementary strands are antiparallel. D) Two hydrogen bonds form between A and T.  
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show the bases occupy the interior of the helix.  
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show nonspecific base-stacking interaction between two adjacent bases in the same strand.  
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show rotation around the sugar-base bond.  
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show right; 20; 3.4  
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show the two strands have complementary sequences.  
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Which of the following is a palindromic sequence?   show
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show hydrogen bonds involving the bases.  
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show can form between two self-complementary regions of the same single strand of RNA.  
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When double-stranded DNA is heated at neutral pH, which change does not occur?   show
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Which of the following deoxyoligonucleotides will hybridize with a DNA containing the sequence (5')AGACTGGTC(3')?   show
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The ribonucleotide polymer (5')GTGATCAAGC(3') could only form a double-stranded structure with:   show
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In comparison with DNA-DNA double helices, the stability of DNA-RNA and RNA-RNA helices is:   show
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show A) oxygen. B) UV light.  
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show deamination of bases.  
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show the role of the dideoxy CTP is to occasionally terminate enzymatic synthesis of DNA where Gs occur in the template strands.  
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show the nucleotide initially attached to the silica gel support will become the 3' end of the finished product.  
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show A) carriers of metabolic energy. B) enzyme cofactors. C) intracellular signals. D) precursors for nucleic acid synthesis.  
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Created by: chemgeek1986