Nucleotides and Nucleic Acids
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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show | adenosine
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show | uracil
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show | a deoxyribonucleotide has an —H instead of an —OH at C-2.
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Which one of the following is TRUE of the pentoses found in nucleic acids? | show 🗑
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show | join the 3' hydroxyl of one nucleotide to the 5' hydroxyl of the next.
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The phosphodiester bond that joins adjacent nucleotides in DNA: | show 🗑
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show | 3',5'-cAMP
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show | A) 2'- AMP
B) 2',3'-cGMP
C) 2'-CMP
D) 3'-UMP
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The DNA oligonucleotide abbreviated pATCGAC: | show 🗑
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show | the nucleotide at the 5' end has a phosphate on its 5' hydroxyl.
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The nucleic acid bases: | show 🗑
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Which of the following statements concerning the tautomeric forms of bases such as uracil is correct? | show 🗑
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In a double-stranded nucleic acid, cytosine typically base-pairs with: | show 🗑
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show | The distance between the two glycosidic (base-sugar) bonds is the same in both base pairs,
within a few tenths of an angstrom.
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The experiment of Avery, MacLeod, and McCarty in which nonvirulent bacteria were made virulent by transformation was significant because it showed that: | show 🗑
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show | A + G = T + C.
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show | absence of 2'-hydroxyl groups allows bases to lie perpendicular to the helical axis.
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show | the distance between two adjacent bases in one strand is about 3.4 Å.
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Which of the following is NOT true of all naturally occurring DNA? | show 🗑
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show | A) Deoxyribose units are connected by 3',5'-phosphodiester bonds.
B) The amount of A always equals the amount of T.
C) The two complementary strands are antiparallel.
D) Two hydrogen bonds form between A and T.
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show | the bases occupy the interior of the helix.
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show | nonspecific base-stacking interaction between two adjacent bases in the same strand.
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show | rotation around the sugar-base bond.
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show | right; 20; 3.4
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show | the two strands have complementary sequences.
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Which of the following is a palindromic sequence? | show 🗑
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show | hydrogen bonds involving the bases.
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show | can form between two self-complementary regions of the same single strand of RNA.
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When double-stranded DNA is heated at neutral pH, which change does not occur? | show 🗑
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Which of the following deoxyoligonucleotides will hybridize with a DNA containing the sequence (5')AGACTGGTC(3')? | show 🗑
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The ribonucleotide polymer (5')GTGATCAAGC(3') could only form a double-stranded structure with: | show 🗑
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In comparison with DNA-DNA double helices, the stability of DNA-RNA and RNA-RNA helices is: | show 🗑
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show | A) oxygen.
B) UV light.
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show | deamination of bases.
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show | the role of the dideoxy CTP is to occasionally terminate enzymatic synthesis of DNA where Gs
occur in the template strands.
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show | the nucleotide initially attached to the silica gel support will become the 3' end of the finished
product.
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show | A) carriers of metabolic energy.
B) enzyme cofactors.
C) intracellular signals.
D) precursors for nucleic acid synthesis.
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Created by:
chemgeek1986