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Quiz yourself by thinking what should be in
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| show | multicellular
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| The maintenance of a constant environment in a cell is called ___________. | show 🗑
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| show | environmental
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| show | regulation
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| Eukaryotic cell mRNA transcripts tend to be very ______ and can remain in the cell for hours. | show 🗑
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| show | enhancer sequences within the DNA.
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| show | major groove of the DNA helix.
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| 9. Vertebrate cells apparently possess a protein that by binding to clusters of 5-methylcytosine ensures that the bound gene will stay in the "off" position. This control on the role of gene regulation is a result of | show 🗑
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| 10. Regulatory proteins shut off transcription by binding to a site immediately in front of the promoter and often even overlapping the promotor. This site is referred to as the | show 🗑
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| show | nucleosomes
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| 12. Which of the following is the hallmark of multicellular organisms | show 🗑
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| 13. Enhancers are the binding sites for the | show 🗑
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| show | transcriptional control.
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| show | 8
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| show | regulatory DNA sequences.
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| show | once a gene is turned off, it will remain off.
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| show | In bacteria it allows them to replicate without control.
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| 19. RNA polymerase binds to a site on DNA called the | show 🗑
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| show | between 21 to 28 nucleotides.
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| show | double stranded RNA interference with mRNA.
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| 22. Proteins that bind to regulatory sequences have shapes that fit into the | show 🗑
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| show | structural motifs.
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| show | TATA box.
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| show | repressor.
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| 26. In gene regulation, a gene is "turned on" by a(n) | show 🗑
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| 27. A bacterial gene regulatory system is likely to have all of the following except | show 🗑
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| show | mRNA to prevent translation.
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| show | is only rarely available; producing enzymes all the time is costly.
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| show | catabolite activator protein (CAP).
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| 31. In eukaryotes, specific transcription factors have two distinct domains: | show 🗑
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| 32. Which of the following must happen for transcription to be initiated? | show 🗑
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| 33. Certain proteins can bind to specific DNA regulatory sequences by | show 🗑
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| 34. Regulatory proteins can identify specific sequences on the DNA double helix without unwinding the helix. This is accomplished by | show 🗑
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| show | trp operon.
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| show | lac operon.
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| show | have their transcription occurring in the nucleus and translation in the cytoplasm.
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| 38. The CAP molecule can attach to the CAP binding site only when the | show 🗑
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| 39. Which of the following statements regarding primary transcripts in eukaryotes is correct? | show 🗑
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| 40. One of the DNA-binding motifs that contains a nearly identical sequence of 60 amino acids in many eukaryotic organisms is known as the | show 🗑
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| show | helix-turn-helix.
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| 42. A protein that regulates transcription by binding to the operator. | show 🗑
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| show | CAP
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| 44. A cluster of functionally-related genes encoded into a mRNA molecule; a mode of prokaryotic gene regulating unit. | show 🗑
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| 45. A site of negative genetic regulation; binding by repressor blocks transcription. | show 🗑
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| 46. A site at the 5' end of a gene to which RNA polymerase attaches to initiate transcription. | show 🗑
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| 47. You are performing a mutagenesis screen to isolate mutations in Drosophila. While looking through a batch of mutagenized flies, you find a fly in which its antenna had been transformed to a pair of extra legs. You surmise that this fly must have a mut | show 🗑
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| 48. The enzyme β-galactosidase acts on lactose to form galactose. In turn, the presence of galactose leads to expression of the enzymes responsible for the metabolism of galactose. In this case, lactose is serving a carbon source and as a(n) | show 🗑
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| 49. The lactose analog isopropyl-β-D-thio-galactoside (IPTG) is often used to regulate gene expression systems in bacteria. IPTG does not act as a substrate for β-galactosidase, but can bind to, and inactivate, repressor. In this case, IPTG serves as a(n) | show 🗑
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| 50. The main form of glucose repression of the lac operon is | show 🗑
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| show | Bacteria preferentially utilize lactose as a carbon source.
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| show | interfere with RNA polymerase binding to the promotor.
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| show | the operon is OFF in the absence of its regulatory protein.
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| 54. In eukaryotes, the binding of TFIID is followed by the binding of a number of other general transcription factors. Which of the following lists the correct order of binding of these factors? | show 🗑
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| show | Since transcription domains can be separated, try to express and purify only the activation domain.
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| 56. You are working to identify enhancer regions of a particular gene. You should look | show 🗑
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| 57. The progesterone receptor (PR) is a steroid hormone receptor and transcription factor. The protein SRC-1, which does not bind DNA by itself, can bind to PR and increase expression of genes regulated by PR. Based on this information, SRC-1 is a(n) | show 🗑
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| show | TATA-binding protein TBP and TAFs.
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| show | Basal factors remain associated with RNA pol II after positioning RNA pol II at the start site.
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| show | chromatin remodeling.
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| 61. DNA methylation is the only known natural modification of DNA. It affects | show 🗑
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| show | be looking at a region of inactive chromatin.
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| 63. Elucidation of the histone code might | show 🗑
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| show | Use RNA interference to prevent mRNA translation.
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| show | miRNA and siRNA.
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| 66. The gene encoding apolipoprotein B exists in two isoforms, APOB100 and APOB48. These two forms are produced as a result of | show 🗑
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| show | translation repressor protein.
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| show | Ubiquitination of a targeted protein requires only one molecule of ATP.
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| 69. What is the difference between a gene that is derepressed and one that is induced? | show 🗑
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Created by:
ClaEsc